HUBUNGAN PENGETAHUAN PENGOBATAN DENGAN KEPATUHAN MINUM OBAT ANTIDIABETES PADA PASIEN DIABETES MELITUS TIPE 2 DI PUSKESMAS PAMOLOKAN SUMENEP

Chronic diseases such as type 2 diabetes mellitus (DM) are increasing in Indonesia, including in East Java and Sumenep Regency. The success of therapy depends on medication adherence, which is influenced, among other factors, by patients' knowledge of their treatment. This study aimed to analyze the relationship between medication knowledge and adherence to antidiabetic medication among patients with type 2 DM at Pamolokan Community Health Center (Puskesmas), Sumenep. An analytic survey with a cross-sectional design was used. A total of 84 patients participated, selected by total sampling in the Prolanis group and simple random sampling in the Non-Prolanis group. Data were collected using a medication knowledge questionnaire and the MMAS-8, and analyzed with the Chi-Square test and Fisher's Exact Test. Respondents were predominantly women (84.5%), aged 19–59 years (53.6%), with elementary school as their highest education (57.1%), and unemployed (59.5%). Most respondents had good medication knowledge (95.2%) and were adherent (70.2%). Because 2 of 4 cells (50%) had expected counts below 5, Fisher's Exact Test was used as the primary inferential result (p = 0.040); the Chi-Square test, reported for comparison, gave p = 0.035. The odds ratio (OR) was 7.909 (95% CI 0.781–80.065); this interval includes 1 and is very wide because only 4 respondents had poor knowledge, so the estimate must be interpreted with caution. In conclusion, there is a significant association between medication knowledge and antidiabetic medication adherence; however, the cross-sectional design does not allow causal inference.