Etiology, pathogenesis, classification, diagnosis and management tactics for patients with hepatic portal hypertension depending on the anatomical features of the portal vein and its tributaries

Portal hypertension (PH) syndrome remains one of the most challenging issues in modern hepatobiliary surgery. The clinical significance of the hepatic form of PH is determined not only by the risk of fatal hemorrhagic complications but also by systemic metabolic disorders. This review systematizes current data on the etiology, pathogenesis, classification, diagnosis, and surgical treatment of hepatic portal hypertension. A literature search was conducted in the PubMed, Scopus, eLibrary, and Google Scholar databases for the period from 2010 to 2025 in both Russian and English. Original studies and systematic reviews relevant to the topic were included. Data analysis emphasizes the importance of early diagnosis, a comprehensive approach to treatment, and multidisciplinary collaboration among specialists to improve clinical outcomes and enhance the quality of life for patients with PH.

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Publication Details

Journal
Экспериментальная и клиническая гастроэнтерология
Published
2026-11-07
DOI
https://doi.org/10.31146/1682-8658-ecg-247-3-147-160
Primary Topic
Liver Disease and Transplantation
Type
article
Field-Weighted Citation Impact
0.00
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article

Etiology, pathogenesis, classification, diagnosis and management tactics for patients with hepatic portal hypertension depending on the anatomical features of the portal vein and its tributaries

Igor V. Makarov, I.V. Kolesnik, V.D. Aksenova, A. S. Efimova
Экспериментальная и клиническая гастроэнтерология
Liver Disease and Transplantation
article

Etiology, pathogenesis, classification, diagnosis and management tactics for patients with hepatic portal hypertension depending on the anatomical features of the portal vein and its tributaries

Igor V. Makarov, I.V. Kolesnik, V.D. Aksenova, A. S. Efimova
article en

Abstract

Portal hypertension (PH) syndrome remains one of the most challenging issues in modern hepatobiliary surgery. The clinical significance of the hepatic form of PH is determined not only by the risk of fatal hemorrhagic complications but also by systemic metabolic disorders. This review systematizes current data on the etiology, pathogenesis, classification, diagnosis, and surgical treatment of hepatic portal hypertension. A literature search was conducted in the PubMed, Scopus, eLibrary, and Google Scholar databases for the period from 2010 to 2025 in both Russian and English. Original studies and systematic reviews relevant to the topic were included. Data analysis emphasizes the importance of early diagnosis, a comprehensive approach to treatment, and multidisciplinary collaboration among specialists to improve clinical outcomes and enhance the quality of life for patients with PH.

Экспериментальная и клиническая гастроэнтерология(3)
Samara State Medical University (RU)
Openalex Percentile: Top 17%
Liver Disease and Transplantation
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