Assessing the impact of gender affirming endocrine interventions on the mental health and well-being among transgender youth

Purpose In the absence of previous systematic longitudinal evidence, this pilot study aims to evaluate the quality of life (QOL) of transgender youth in relation to several other psychological variables impacting the mental health of youth. Design/methodology/approach The cross-sectional descriptive study, conducted as a small-scale trial run, examined several mental health variables such as stress, anxiety, depression, social support, resilience and self-efficacy influencing the QOL of the transgender youth. The participants were assessed for relevant, detailed demographic and clinical information, along with a semi-structured questionnaire. Findings The pilot study included 50 transgenders between 18 and 25 years age category, categorized as youth. Descriptive data indicated the diversity in the demography and perception of transgender individuals about the gender-affirming care received during transitions. The favorable scores of Cronbach’s alpha indicated that the tool is highly reliable for measuring the intended objectives. Low scores of depression, anxiety and stress indicate a good QOL among the youth. Further results also indicate that the gender affirmation care received has a greater impact on the mental health variables that determine the self-identity of the trans individuals. Originality/value Mental health plays a critical role in determining the QOL of transgenders. Therefore, studying the longitudinal impact on suitable gender-affirming endocrine interventions can provide a foundation for drawing evidence-based health care practices and policies to protect the transgender youth, thereby promoting their effective functioning in the society.

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Publication Details

Journal
Mental Health and Social Inclusion
Published
2026-11-09
DOI
https://doi.org/10.1108/mhsi-08-2026-0312
Primary Topic
LGBTQ Health, Identity, and Policy
Type
article
Field-Weighted Citation Impact
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article

Assessing the impact of gender affirming endocrine interventions on the mental health and well-being among transgender youth

Bhavik M. Panchasara, C. Vijayalakshmi, S. Visalakshmi, Remya Lathabhavan et al.
Mental Health and Social Inclusion
LGBTQ Health, Identity, and Policy
article

Assessing the impact of gender affirming endocrine interventions on the mental health and well-being among transgender youth

Bhavik M. Panchasara, C. Vijayalakshmi, S. Visalakshmi, Remya Lathabhavan, P. Venkataraman, Saranya Sundarraju, K. Hariharan, S. Srividhya, T. Siva Vijayakumar
article en

Abstract

Purpose In the absence of previous systematic longitudinal evidence, this pilot study aims to evaluate the quality of life (QOL) of transgender youth in relation to several other psychological variables impacting the mental health of youth. Design/methodology/approach The cross-sectional descriptive study, conducted as a small-scale trial run, examined several mental health variables such as stress, anxiety, depression, social support, resilience and self-efficacy influencing the QOL of the transgender youth. The participants were assessed for relevant, detailed demographic and clinical information, along with a semi-structured questionnaire. Findings The pilot study included 50 transgenders between 18 and 25 years age category, categorized as youth. Descriptive data indicated the diversity in the demography and perception of transgender individuals about the gender-affirming care received during transitions. The favorable scores of Cronbach’s alpha indicated that the tool is highly reliable for measuring the intended objectives. Low scores of depression, anxiety and stress indicate a good QOL among the youth. Further results also indicate that the gender affirmation care received has a greater impact on the mental health variables that determine the self-identity of the trans individuals. Originality/value Mental health plays a critical role in determining the QOL of transgenders. Therefore, studying the longitudinal impact on suitable gender-affirming endocrine interventions can provide a foundation for drawing evidence-based health care practices and policies to protect the transgender youth, thereby promoting their effective functioning in the society.

Mental Health and Social Inclusion
Central University of Tamil Nadu (IN), SRM Institute of Science and Technology (IN), Saurashtra University (IN), Indian Institute of Management Bodh Gaya (IN), Dhanalakshmi Srinivasan University (IN), SASTRA University (IN)
Good health and well-being, Reduced inequalities
LGBTQ Health, Identity, and Policy
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