Liver damage due to hemochromatosis
The article presents a clinical case of hemochromatosis diagnosis with the presence of a heterozygous HFE His63Asp (H63D) mutation in a patient with liver damage. In our opinion, the reason leading to secondary iron retention in this case was the long-term intake of allopurinol. Correction of urate-lowering therapy led to a decrease in ferritin levels and normalization of liver parameters.
Authors
- A. A. Markova (ORCID: https://orcid.org/0000-0001-8561-2214)
- Elena Igorevna Kashkina (ORCID: https://orcid.org/0000-0003-4347-9974)
- Апаркина Алена Васильевна (ORCID: https://orcid.org/0000-0001-8463-2379)
Institutions
- Saratov State Medical University (RU)
Publication Details
- Journal
- Экспериментальная и клиническая гастроэнтерология
- Published
- 2026-11-07
- DOI
- https://doi.org/10.31146/1682-8658-ecg-247-3-178-182
- Primary Topic
- Iron Metabolism and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00