Acute Ocular Keratopathy Secondary to Calotropis Latex Exposure: A Case Report in the United Arab Emirates

Ocular exposure to Calotropis procera latex is an uncommon but clinically significant cause of toxic keratopathy, particularly in regions where the plant is endemic.The latex contains bioactive compounds capable of inducing corneal endothelial dysfunction and stromal edema, often with minimal epithelial involvement.We report a case of a 27-year-old male who presented with acute-onset redness, pain, and blurred vision in the right eye following accidental exposure to Calotropis procera latex.Initial examination revealed reduced visual acuity (6/24), conjunctival congestion, superficial punctate keratitis, and a quiet anterior chamber.Imaging with anterior segment optical coherence tomography and specular microscopy supported corneal involvement.After medical management, rapid clinical improvement was observed, with visual acuity improving to 6/9 within 24 hours and complete recovery to 6/6 within one week.Resolution of corneal edema, Descemet's folds, and conjunctival congestion was noted, with complete recovery at three weeks follow-up and no residual sequelae.Calotropis procera latex exposure can result in reversible toxic keratopathy, which should be treated with prompt irrigation and early initiation of topical corticosteroid therapy.Increased awareness is essential in regions where the plant is prevalent, including the Middle East.

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Publication Details

Journal
Cureus
Published
2026-11-07
DOI
https://doi.org/10.7759/cureus.119294
Primary Topic
Traumatic Ocular and Foreign Body Injuries
Type
article
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article

Acute Ocular Keratopathy Secondary to Calotropis Latex Exposure: A Case Report in the United Arab Emirates

Simanta Khadka, Thuslim Sheik, Gargi Sharma, Marriam Tasneem
Cureus
Traumatic Ocular and Foreign Body Injuries
article

Acute Ocular Keratopathy Secondary to Calotropis Latex Exposure: A Case Report in the United Arab Emirates

Simanta Khadka, Thuslim Sheik, Gargi Sharma, Marriam Tasneem
article en

Abstract

Ocular exposure to Calotropis procera latex is an uncommon but clinically significant cause of toxic keratopathy, particularly in regions where the plant is endemic.The latex contains bioactive compounds capable of inducing corneal endothelial dysfunction and stromal edema, often with minimal epithelial involvement.We report a case of a 27-year-old male who presented with acute-onset redness, pain, and blurred vision in the right eye following accidental exposure to Calotropis procera latex.Initial examination revealed reduced visual acuity (6/24), conjunctival congestion, superficial punctate keratitis, and a quiet anterior chamber.Imaging with anterior segment optical coherence tomography and specular microscopy supported corneal involvement.After medical management, rapid clinical improvement was observed, with visual acuity improving to 6/9 within 24 hours and complete recovery to 6/6 within one week.Resolution of corneal edema, Descemet's folds, and conjunctival congestion was noted, with complete recovery at three weeks follow-up and no residual sequelae.Calotropis procera latex exposure can result in reversible toxic keratopathy, which should be treated with prompt irrigation and early initiation of topical corticosteroid therapy.Increased awareness is essential in regions where the plant is prevalent, including the Middle East.

Cureus
Gulf Medical University (AE)
Openalex Percentile: Top 12%
Traumatic Ocular and Foreign Body Injuries
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Acute Ocular Keratopathy Secondary to Calotropis Latex Exposure: A Case Report in the United Arab Emirates — Simanta Khadka, Thuslim Sheik, et al. · Cureus (2026) | TGRS Research Map | TGRS