EIN-RECAP: Evidence-Grounded Multi-Agent Summarization and Retrieval of Infectious-Disease Expert Discussions

Infectious disease experts exchange practical knowledge through clinical discussions, but identifying relevant information across years of conversations is difficult. These discussions often contain differing opinions and emerging observations that are not yet reflected in published evidence. We present EIN-RECAP, an AI-assisted platform developed with Emerging Infections Network (EIN) experts and deployed in beta to summarize and search historical discussions. The system combines retrieval-grounded summarization, citation validation, and hybrid search while distinguishing published evidence from community experience. We evaluated summarization methods across 3,185 threads and conducted blinded expert review on a recent subset. Although a multi-agent workflow achieved stronger automated scores, experts favored a simpler generation pipeline and identified repetition, inaccuracies, and overconfident recommendations in the more complex system. This feedback motivated an ensemble that improved discussion coverage and key clinical points on nine high-disagreement threads, although retrieval relevance remained a limitation. Our findings demonstrate the importance of expert involvement in clinical AI development and show why automated evaluation alone is insufficient to guide system selection.

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Publication Details

Journal
medRxiv
Published
2026-11-06
DOI
https://doi.org/10.64898/2026.11.05.26367381
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
preprint
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preprint

EIN-RECAP: Evidence-Grounded Multi-Agent Summarization and Retrieval of Infectious-Disease Expert Discussions

Akash Choudhuri, Jacob Hodges, Susan E. Beekmann, Kishlay Jha et al.
medRxiv
Artificial Intelligence in Healthcare and Education
preprint

EIN-RECAP: Evidence-Grounded Multi-Agent Summarization and Retrieval of Infectious-Disease Expert Discussions

Akash Choudhuri, Jacob Hodges, Susan E. Beekmann, Kishlay Jha, Bijaya Adhikari, Alberto M. Segre, Yongjian Zhong, Philip M Polgreen
preprint en

Abstract

Infectious disease experts exchange practical knowledge through clinical discussions, but identifying relevant information across years of conversations is difficult. These discussions often contain differing opinions and emerging observations that are not yet reflected in published evidence. We present EIN-RECAP, an AI-assisted platform developed with Emerging Infections Network (EIN) experts and deployed in beta to summarize and search historical discussions. The system combines retrieval-grounded summarization, citation validation, and hybrid search while distinguishing published evidence from community experience. We evaluated summarization methods across 3,185 threads and conducted blinded expert review on a recent subset. Although a multi-agent workflow achieved stronger automated scores, experts favored a simpler generation pipeline and identified repetition, inaccuracies, and overconfident recommendations in the more complex system. This feedback motivated an ensemble that improved discussion coverage and key clinical points on nine high-disagreement threads, although retrieval relevance remained a limitation. Our findings demonstrate the importance of expert involvement in clinical AI development and show why automated evaluation alone is insufficient to guide system selection.

medRxiv
University of Iowa (US)
Artificial Intelligence in Healthcare and Education
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