Soft tissue mechanics reproducibility and prediction plan

Approved analysis plan for a secondary analysis of porcine spinal-cord mechanical measurements. The study will audit how explicit constitutive, fixation, and indentation-processing choices affect held-out force predictions, and will release a checked mechanical specification and reproducibility flags. It specifies a primary bulk prediction test and secondary mapping and sensitivity-envelope tests, including fixed rules for failure and non-evaluability. The plan was approved before constitutive tissue fitting. Earlier exploratory data summaries and source-equation discrepancies were already known and are not retrospectively preregistered. This deposit contains the approved plan, machine-readable protocol and prediction rules, and content hashes; it contains no empirical model results or original raw dataset. Source dataset: https://doi.org/10.5281/zenodo.17152951. Source article: https://doi.org/10.1016/j.actbio.2026.04.036. Numerical forward-model verification is required before empirical fitting. This is a timestamped analysis-plan archive, not a registered report or completed validation study. The deposit is the plan and specification subset; the Availability section also describes separate project review records that are not included in this public archive.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-11-07
DOI
https://doi.org/10.5281/zenodo.24025543
Primary Topic
Elasticity and Material Modeling
Type
article
Field-Weighted Citation Impact
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article

Soft tissue mechanics reproducibility and prediction plan

Luke Yin, Cooper Lee, Adam Park, Yoo Choi et al.
1 links
Zenodo (CERN European Organization for Nuclear Research)
Elasticity and Material Modeling
article

Soft tissue mechanics reproducibility and prediction plan

Luke Yin, Cooper Lee, Adam Park, Yoo Choi, Andrew Wong
article en

Abstract

Approved analysis plan for a secondary analysis of porcine spinal-cord mechanical measurements. The study will audit how explicit constitutive, fixation, and indentation-processing choices affect held-out force predictions, and will release a checked mechanical specification and reproducibility flags. It specifies a primary bulk prediction test and secondary mapping and sensitivity-envelope tests, including fixed rules for failure and non-evaluability. The plan was approved before constitutive tissue fitting. Earlier exploratory data summaries and source-equation discrepancies were already known and are not retrospectively preregistered. This deposit contains the approved plan, machine-readable protocol and prediction rules, and content hashes; it contains no empirical model results or original raw dataset. Source dataset: https://doi.org/10.5281/zenodo.17152951. Source article: https://doi.org/10.1016/j.actbio.2026.04.036. Numerical forward-model verification is required before empirical fitting. This is a timestamped analysis-plan archive, not a registered report or completed validation study. The deposit is the plan and specification subset; the Availability section also describes separate project review records that are not included in this public archive.

Zenodo (CERN European Organization for Nuclear Research)
Princeton University (US), Illinois Mathematics and Science Academy (US)
Openalex Percentile: Top 27%
Elasticity and Material Modeling
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