Divinely Created Biological Regulatory Architecture (DCBRA): An Integrated Cross-System Analytical Framework

Divinely Created Biological Regulatory Architecture (DCBRA): An Integrated Cross-System Analytical Framework Author: Dr. S. M. Habibur Rahman Consultant Physician in Medicine, Diabetes & Hormone Diseases | Ibn Sina Hospital & Diagnostic Center, Bogura, Bangladesh ORCID: https://orcid.org/0009-0006-1678-7380 Proposed Bengali Rendering: আল্লাহ-প্রদত্ত মানবদেহের জৈবিক নিয়ন্ত্রণ ও সমন্বয়ব্যবস্থা Version: 1.1 | Date: 07 November 2026 Abstract: Biological regulation across molecular, cellular, and organismal scales is frequently studied within compartmentalized physiological domains. This paper presents the foundational architecture and methodological scope of the Divinely Created Biological Regulatory Architecture (DCBRA), a proposed integrative framework developed to map diverse biological processes through a standardized five-stage analytical scaffold: Recognition, Signal Transmission, Integration, Activation, and Regulation/Feedback. Acknowledging that biological systems operate non-linearly and across overlapping scales, DCBRA introduces a Stage x Scale x Regulatory Mode matrix alongside a cross-system taxonomy of regulatory failure. Pilot domains including glucose-insulin homeostasis, innate and adaptive immunity, and cutaneous wound repair are evaluated. The framework explicitly separates the author's theological worldview—expressed via the term 'Divinely Created'—from measurable empirical variables, framing DCBRA not as an established biological law, but as a reproducible cross-domain mapping protocol intended to enhance analytical clarity and hypothesis generation.