Vancomycin Renal Feedback 100k — Sample and Documentation

This upload contains the full technical documentation and a free evaluation sample (1,000 patients from each table, both scenarios, 21 files, 4.8 MB uncompressed) — not the full dataset. Full dataset (200,000 patients, 18 tables, ~343 MB): https://sentineldata.com.ua/dataset/vancomycin-renal-feedback-100k Sample contents Scenario Files Patients A 9 Parquet tables (cohort, observed, observed_outcomes, truth, truth_traj, truth_counterfactual, truth_noloop, truth_exposure_daily, regime_arms) 1,000 per table (3,000 for regime_arms) B 9 Parquet tables (same set) 1,000 per table (3,000 for regime_arms) Also included: HOW_TO_OPEN_PARQUET.txt, manifest_sha256.csv, English sample passport PDF. The sample is a true, unmodified subset of the full dataset: patient_id 1–1000 of each patient-level table, their hourly trajectories, and 1,000 subjects from each of the three regimen cohorts, for both scenarios. What is this dataset Vancomycin is excreted by the kidneys and injures the tubules, so exposure acts on its own elimination. In published population PK models and dosing programs, renal function is a covariate fed in from outside. Here it is a state variable: the loop is closed inside the equations. The cohort is 100,000 virtual adult inpatients whose baseline creatinine, ICU share, age and treatment duration match those of 128,993 real vancomycin-treated patients. Two calibrated ... Full description with all tables is on the Wiki page of this project. Full dataset and purchase: https://sentineldata.com.ua/dataset/vancomycin-renal-feedback-100k . Zenodo copy: https://doi.org/10.5281/zenodo.23210397

Authors

Publication Details

Journal
Open Science Framework
Published
2026-11-07
DOI
https://doi.org/10.17605/osf.io/5yguz
Primary Topic
Antibiotics Pharmacokinetics and Efficacy
Type
article
Field-Weighted Citation Impact
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article

Vancomycin Renal Feedback 100k — Sample and Documentation

Chekerskyi Maksym
3 links
Open Science Framework
Antibiotics Pharmacokinetics and Efficacy
article

Vancomycin Renal Feedback 100k — Sample and Documentation

Chekerskyi Maksym
article en

Abstract

This upload contains the full technical documentation and a free evaluation sample (1,000 patients from each table, both scenarios, 21 files, 4.8 MB uncompressed) — not the full dataset. Full dataset (200,000 patients, 18 tables, ~343 MB): https://sentineldata.com.ua/dataset/vancomycin-renal-feedback-100k Sample contents Scenario Files Patients A 9 Parquet tables (cohort, observed, observed_outcomes, truth, truth_traj, truth_counterfactual, truth_noloop, truth_exposure_daily, regime_arms) 1,000 per table (3,000 for regime_arms) B 9 Parquet tables (same set) 1,000 per table (3,000 for regime_arms) Also included: HOW_TO_OPEN_PARQUET.txt, manifest_sha256.csv, English sample passport PDF. The sample is a true, unmodified subset of the full dataset: patient_id 1–1000 of each patient-level table, their hourly trajectories, and 1,000 subjects from each of the three regimen cohorts, for both scenarios. What is this dataset Vancomycin is excreted by the kidneys and injures the tubules, so exposure acts on its own elimination. In published population PK models and dosing programs, renal function is a covariate fed in from outside. Here it is a state variable: the loop is closed inside the equations. The cohort is 100,000 virtual adult inpatients whose baseline creatinine, ICU share, age and treatment duration match those of 128,993 real vancomycin-treated patients. Two calibrated ... Full description with all tables is on the Wiki page of this project. Full dataset and purchase: https://sentineldata.com.ua/dataset/vancomycin-renal-feedback-100k . Zenodo copy: https://doi.org/10.5281/zenodo.23210397

Open Science Framework
Good health and well-being
Openalex Percentile: Top 19%
Antibiotics Pharmacokinetics and Efficacy
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