Tröger’s Base-Containing Pillararenes: Skeletal Reshaping via Local Rigid Geometric Confinement
Abstract Pillar[1]Trögerbase[n]arenes (P[1]TB[n]As, where n = 4, 5, and 6) were constructed through the combination of pillar[6,7,8]arenes with geometrically mismatched Tröger’s base (TB) units. TB induced pronounced skeleton distortion, forming P[1]TB[n]As with specific cavity shapes. A skeleton-simplified P[1]TB[5]A analogue was also obtained. This work provides a rare case of skeletal modification of pillar[7,8]arenes and verifies that local rigid geometric confinement could directionally reshape macrocyclic structures, offering new strategies for supramolecular host design.
Authors
- Can Jin (ORCID: https://orcid.org/0000-0003-1997-6209)
- Lin Chen (ORCID: https://orcid.org/0000-0002-4160-8077)
- Conghao Shi
- Juli Jiang (ORCID: https://orcid.org/0000-0001-5778-6380)
- Yong Fang Liang (ORCID: https://orcid.org/0000-0001-5026-6710)
- Wang Xie (ORCID: https://orcid.org/0009-0003-6627-9702)
- Leyong Wang (ORCID: https://orcid.org/0000-0001-5775-3714)
- Yang Zhou (ORCID: https://orcid.org/0000-0003-4477-6532)
- Wei Huang (ORCID: https://orcid.org/0000-0002-1071-1055)
- Guangzhou Xu
- Ranran Wang
Institutions
- Chinese Academy of Forestry (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2026-11-06
- DOI
- https://doi.org/10.1021/acs.orglett.6c04308
- Primary Topic
- Supramolecular Chemistry and Complexes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province