Sealing ability of two calcium silicate based experimental materials in furcation perforation repair: An in vitro study

Aim The purpose of this vitro study was the comparison of the sealing ability of two experimental calcium silicate /calcium aluminate-based nano materials. Materials and methods Sealing of intentionally done perforation in the furcation area in ninety extracted mandibular molars was performed using in group 1(n = 20): Biodentine, in group 2 (n = 20): experimental material A (NanoTricalcium silicate, Nano Dicalcium silicateand Nano Calcium Aluminate based material), in group 3 (n = 20): experimental material B (NanoTricalcium silicate and Nano Calcium Aluminate based material), in Group 4 (n = 20): MTA Angelus and in Group 5: Negative Control (n = 10): No repair material or coronal seal was placed, leaving the perforation site open, to ensure the dye could freely pass through the perforation. Dye penetration test was then done using 1% methylene blue dye solution, followed by recording values of dye penetration using stereomicroscope at magnification 25X. One-way ANOVA followed by Tukey post hoc test was applied to compare more than two groups in non-related samples. Results Biodentine recorded the lowest mean leakage value (8.192 ± 0.447 mm) with no statistically significant difference with both experimental A and MTA groups, which recorded mean leakage value (8.596 ± 0.580 mm) and (8.330 ± 0.916 mm) respectively. Experimental B recorded the highest mean leakage value (14.492 ± 0.459 mm) with statistically significant difference with the other three tested materials, where ( p < 0.001). Conclusions According to this in vitro study condition, that differs from the clinical situation, the experimental material A (NanoTricalcium silicate, Nano Dicalcium silicate and Nano Calcium Aluminate based material) showed promising sealing ability outcomes, while the experimental material B (NanoTricalcium silicate and Nano calcium aluminate-based material) showed inferior sealing performance, when both were compared to Biodentine and MTA Angelus.