Neura: Statistical Analysis and Sample-Size Software for Health-Science Research — Methods and Validation Report

Neura is a web-based tool that helps master's and doctoral students in the health sciences plan andreport the quantitative parts of their research: sample-size calculation, statistical analysis of their data,meta-analysis and diagnostic-accuracy statistics. This report describes the statistical methods Neurauses, the software libraries behind them, the role and limits of artificial intelligence (AI) in the tool, andhow the numerical results were validated against independent references. All reported numbers areproduced by deterministic, published statistical methods; AI is used only to help choose a suitablemethod and to describe results in plain language. In the current validation suite, Neura reproduced theexpected answers in all 48 test cases (90 of 90 numeric checks), including 17 sample-size cases checkedagainst G*Power 3.1 and 6 meta-analysis cases checked against the published metafor results.