Premature Ovarian Insufficiency in Primary Care: A Scoping Review of Recognition, Diagnostic Delay and Interdisciplinary Care Pathways

Background/Objectives: Premature ovarian insufficiency (POI) affects approximately 3.5% of women with lifelong bone, cardiovascular, psychological and reproductive consequences. International guidance assigns primary care important roles in recognition, diagnosis and follow-up. This review mapped evidence across the POI care continuum. Methods: Following Joanna Briggs Institute methodology and PRISMA-ScR, PubMed/MEDLINE, Scopus and Web of Science were searched from inception to 4 October 2026. Two reviewers independently screened records and assessed full texts. Data were charted by one reviewer, verified by a second and synthesised across five domains. Results: Of 1327 records (806 after deduplication), 91 full texts were assessed and 53 sources included (31 empirical; 22 secondary/prescriptive). Primary-care guidance was common, but empirical evidence from primary care was limited. Diagnostic delay of months to years was reported, and in one survey more than half of women consulted three or more clinicians before diagnosis. In one physician survey, supported by a smaller pilot survey, primary care physicians initiated hormone therapy less often than specialists, and gaps in long-term follow-up persisted. No formally evaluated shared-care model was identified. Conclusions: Primary care is central to recommended POI care, but implementation remains poorly studied. Research should quantify real-world primary care performance and test structured interdisciplinary pathways.

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Journal
Healthcare
Published
2026-11-06
DOI
https://doi.org/10.3390/healthcare14213795
Primary Topic
Ovarian function and disorders
Type
article
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article

Premature Ovarian Insufficiency in Primary Care: A Scoping Review of Recognition, Diagnostic Delay and Interdisciplinary Care Pathways

Cristian Nicolae Sava, Alin Bodog, Laura Maghiar, Luana Seles et al.
2 links
Healthcare
Ovarian function and disorders
article

Premature Ovarian Insufficiency in Primary Care: A Scoping Review of Recognition, Diagnostic Delay and Interdisciplinary Care Pathways

Cristian Nicolae Sava, Alin Bodog, Laura Maghiar, Luana Seles, Teodor Andrei Maghiar, Ioana Adelina Faur, Ciprian-Nicușor Solomon, Carmen Anca Huniadi, Iulia Silcău, Irina Daniela Henegariu
article en

Abstract

Background/Objectives: Premature ovarian insufficiency (POI) affects approximately 3.5% of women with lifelong bone, cardiovascular, psychological and reproductive consequences. International guidance assigns primary care important roles in recognition, diagnosis and follow-up. This review mapped evidence across the POI care continuum. Methods: Following Joanna Briggs Institute methodology and PRISMA-ScR, PubMed/MEDLINE, Scopus and Web of Science were searched from inception to 4 October 2026. Two reviewers independently screened records and assessed full texts. Data were charted by one reviewer, verified by a second and synthesised across five domains. Results: Of 1327 records (806 after deduplication), 91 full texts were assessed and 53 sources included (31 empirical; 22 secondary/prescriptive). Primary-care guidance was common, but empirical evidence from primary care was limited. Diagnostic delay of months to years was reported, and in one survey more than half of women consulted three or more clinicians before diagnosis. In one physician survey, supported by a smaller pilot survey, primary care physicians initiated hormone therapy less often than specialists, and gaps in long-term follow-up persisted. No formally evaluated shared-care model was identified. Conclusions: Primary care is central to recommended POI care, but implementation remains poorly studied. Research should quantify real-world primary care performance and test structured interdisciplinary pathways.

HealthcareVol. 14(21)
University of Oradea (RO), Arad County Clinical Hospital (RO), Spitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara (RO), Victor Babeș University of Medicine and Pharmacy Timișoara (RO)
Good health and well-being
Openalex Percentile: Top 14%
Ovarian function and disorders
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