Role of Autologous Platelet-rich plasma (APRP) in wound healing

Chronic non-healing wounds remain a significant therapeutic challenge, particularly in patients with impaired tissue repair. This retrospective study evaluated the efficacy of autologous platelet-rich plasma (PRP) as an adjunctive treatment for promoting wound healing and tissue regeneration. PRP application was associated with improved granulation-tissue formation, accelerated epithelialization and a progressive reduction in wound dimensions. Improvement in wound-bed quality also facilitated progression toward definitive wound closure. These findings suggest that autologous PRP is a potentially safe and effective adjunct in the management of chronic non-healing wounds. By augmenting the physiological healing cascade, PRP may improve clinical outcomes, particularly in patients with compromised wound-healing capacity.