Generalized Integral Transform Modeling of Complex Coupled-Field Transport in Two-Dimensional Keller–Segel Chemotaxis: Verification, Spectral Convergence, and Self-Similar Localization

Complex engineering systems often involve interacting transport fields in which diffusion, field-driven fluxes, production or decay, and nonlinear feedback jointly control stability, transport, and localization.Although originating in mathematical biology, the Keller-Segel system is a canonical coupled-field transport model with this structure and provides a stringent benchmark for computational methodologies aimed at complex and multiphysics transport problems.A multidimensional hybrid numerical-analytical formulation based on the Generalized Integral Transform Technique (GITT) is developed for a parabolic-parabolic Keller-Segel system with homogeneous Neumann boundary conditions.Spatial averages are treated analytically, zero-mean fields are expanded in normalized Neumann eigenfunctions, and exact cosine-product selection rules generate a sparse nonlinear modal system.The transformed equations are advanced using CVODE, a variable-step, variable-order ordinary differential equation (ODE) solver from the SUNDIALS (Suite of Nonlinear and Differential/Algebraic Equation Solvers) package, with variable-order backward differentiation formulas (BDF), together with a matrix-free scaled preconditioned generalized minimal residual (SPGMR) solver in two dimensions.Systematic one-and two-dimensional convergence studies are performed for chemotactic sensitivities χ = 1-5 and are complemented by independent conservative finite-volume/method-of-lines solutions in physical space.The finite-volume discretizations exhibit second-order self-convergence and closely reproduce the converged GITT fields.The parametric study quantifies the transition from weak relaxation to strong aggregation and the growth of genuinely two-dimensional mixed modes.For χ = 5, successive truncations up to 7,920 spatial modes (15,840 coupled ODEs) resolve a strongly localized regime.Physical and spectral localization scales contract consistently, while normalized profiles collapse onto an approximately invariant shape.Independent late-time extrapolations yield characteristic times clustered near t ≈ 2.184.The results demonstrate a high-resolution hybrid framework for nonlinear coupled-field partial differential equation (PDE) systems with cross-field transport, evolving localization, and demanding multiscale resolution, while providing numerical evidence compatible with possible finite-time singularization without constituting a mathematical proof of blow-up.

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Journal
Journal of Complex and Multiphysics Engineering Systems
Published
2026-11-06
DOI
https://doi.org/10.56578/jcmes020103
Primary Topic
Mathematical Biology Tumor Growth
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article
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article

Generalized Integral Transform Modeling of Complex Coupled-Field Transport in Two-Dimensional Keller–Segel Chemotaxis: Verification, Spectral Convergence, and Self-Similar Localization

João Nazareno Nonato Quaresma, Bruno Marques Viegas, Emanuel Negrão Macêdo, Carlos H.R. Moura et al.
Journal of Complex and Multiphysics Engineering Systems
Mathematical Biology Tumor Growth
article

Generalized Integral Transform Modeling of Complex Coupled-Field Transport in Two-Dimensional Keller–Segel Chemotaxis: Verification, Spectral Convergence, and Self-Similar Localization

João Nazareno Nonato Quaresma, Bruno Marques Viegas, Emanuel Negrão Macêdo, Carlos H.R. Moura, Eenato M. Cotta, Alberto M.G. Tolentino, Kalysta O.R. Borges
article en

Abstract

Complex engineering systems often involve interacting transport fields in which diffusion, field-driven fluxes, production or decay, and nonlinear feedback jointly control stability, transport, and localization.Although originating in mathematical biology, the Keller-Segel system is a canonical coupled-field transport model with this structure and provides a stringent benchmark for computational methodologies aimed at complex and multiphysics transport problems.A multidimensional hybrid numerical-analytical formulation based on the Generalized Integral Transform Technique (GITT) is developed for a parabolic-parabolic Keller-Segel system with homogeneous Neumann boundary conditions.Spatial averages are treated analytically, zero-mean fields are expanded in normalized Neumann eigenfunctions, and exact cosine-product selection rules generate a sparse nonlinear modal system.The transformed equations are advanced using CVODE, a variable-step, variable-order ordinary differential equation (ODE) solver from the SUNDIALS (Suite of Nonlinear and Differential/Algebraic Equation Solvers) package, with variable-order backward differentiation formulas (BDF), together with a matrix-free scaled preconditioned generalized minimal residual (SPGMR) solver in two dimensions.Systematic one-and two-dimensional convergence studies are performed for chemotactic sensitivities χ = 1-5 and are complemented by independent conservative finite-volume/method-of-lines solutions in physical space.The finite-volume discretizations exhibit second-order self-convergence and closely reproduce the converged GITT fields.The parametric study quantifies the transition from weak relaxation to strong aggregation and the growth of genuinely two-dimensional mixed modes.For χ = 5, successive truncations up to 7,920 spatial modes (15,840 coupled ODEs) resolve a strongly localized regime.Physical and spectral localization scales contract consistently, while normalized profiles collapse onto an approximately invariant shape.Independent late-time extrapolations yield characteristic times clustered near t ≈ 2.184.The results demonstrate a high-resolution hybrid framework for nonlinear coupled-field partial differential equation (PDE) systems with cross-field transport, evolving localization, and demanding multiscale resolution, while providing numerical evidence compatible with possible finite-time singularization without constituting a mathematical proof of blow-up.

Journal of Complex and Multiphysics Engineering SystemsVol. 2(1)
Universidade do Estado do Pará (BR), Universidade Federal do Pará (BR)
Openalex Percentile: Top 17%
Mathematical Biology Tumor Growth
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