An ocular manifestation of hand, foot and mouth disease

Objective: This report details an atypical presentation of hand, foot, and mouth disease (HFMD) in a 35-year-old female. Method: The patient presented with acute unilateral painless central vision loss with recent coryzal symptoms and a vesicular rash on her hands and feet. Investigation revealed retinal pigment epithelium (RPE) disruption and subretinal thickening infero-nasally to the fovea. Results: Orbital corticosteroids were successfully administered. The investigative and management approach has been compared to that of similar cases available in the literature. Conclusion: This report summarises a case report and a review of available literature on HFMD associated maculopathy, providing an overview on the condition.

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Publication Details

Journal
GMS ophthalmology cases
Published
2026-11-06
DOI
https://doi.org/10.3205/oc000272
Primary Topic
Retinal and Optic Conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

An ocular manifestation of hand, foot and mouth disease

Gabriella Quiney, Sam Kanavati
GMS ophthalmology cases
Retinal and Optic Conditions
article

An ocular manifestation of hand, foot and mouth disease

Gabriella Quiney, Sam Kanavati
article en

Abstract

Objective: This report details an atypical presentation of hand, foot, and mouth disease (HFMD) in a 35-year-old female. Method: The patient presented with acute unilateral painless central vision loss with recent coryzal symptoms and a vesicular rash on her hands and feet. Investigation revealed retinal pigment epithelium (RPE) disruption and subretinal thickening infero-nasally to the fovea. Results: Orbital corticosteroids were successfully administered. The investigative and management approach has been compared to that of similar cases available in the literature. Conclusion: This report summarises a case report and a review of available literature on HFMD associated maculopathy, providing an overview on the condition.

GMS ophthalmology cases
Brighton and Sussex Medical School (GB), Worthing Hospital (GB), Southlands Hospital (GB)
Good health and well-being
Openalex Percentile: Top 10%
Retinal and Optic Conditions
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