Correlation between clinical severity, dermoscopic findings and high frequency ultrasonographic changes in patients with chronic plaque psoriasis: a prospective cross-sectional observational study

Background Chronic plaque psoriasis is an immune-mediated inflammatory disorder characterised by epidermal hyperproliferation and changes in the superficial dermal vasculature. The Psoriasis Area and Severity Index (PASI) quantifies overall clinical disease burden but does not directly measure the microvascular and structural characteristics of an individual plaque. Dermoscopy and high-frequency ultrasonography (HFUS) may provide complementary, non-invasive information. Objectives To assess the relationships between clinical severity, dermoscopic features and HFUS measurements in adults with chronic plaque psoriasis.