NETWORK PHARMACOLOGY: A STUDY OF MULTITARGETED DRUG DELIVERY OF MORINGA OLEIFERA

Moringa oleifera Lam., commonly known as the drumstick tree, is a highly nutritious medicinal plant belonging to the family Moringaceae. It has gained considerable scientific attention due to its rich nutritional composition and diverse pharmacological properties. Various parts of the plant, particularly the leaves, seeds, flowers and pods, contain essential vitamins, minerals, amino acids and several bioactive phytoconstituents, including flavonoids, phenolic compounds, alkaloids, glucosinolates, isothiocyanates and terpenoids. These phytochemicals contribute to its reported antioxidant, antidiabetic, anticancer, antiviral, anti-inflammatory and antihypertensive activities. Recent advancements in network pharmacology have provided valuable insights into the complex interactions between Moringa-derived phytochemicals and multiple molecular targets involved in disease pathways. Computational approaches such as molecular docking, target prediction and pathway enrichment analysis have helped identify potential mechanisms of action, particularly in insulin resistance, cancer and inflammatory disorders. This review highlights the nutritional significance, cultivation, processing methods, phytochemical composition and major pharmacological activities of Moringa oleifera, with particular emphasis on its molecular mechanisms and therapeutic potential. Although existing preclinical and computational findings are promising, further experimental validation and well-designed clinical studies are necessary to establish its safety, efficacy and clinical applications.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-11-05
DOI
https://doi.org/10.5281/zenodo.23972620
Primary Topic
Moringa oleifera research and applications
Type
article
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article

NETWORK PHARMACOLOGY: A STUDY OF MULTITARGETED DRUG DELIVERY OF MORINGA OLEIFERA

Vikas Rajbhar, Sneha Pawar, Binith Raj, shrutika patil et al.
Zenodo (CERN European Organization for Nuclear Research)
Moringa oleifera research and applications
article

NETWORK PHARMACOLOGY: A STUDY OF MULTITARGETED DRUG DELIVERY OF MORINGA OLEIFERA

Vikas Rajbhar, Sneha Pawar, Binith Raj, shrutika patil, Adesh Sawant, Ishika Puralkar
article en

Abstract

Moringa oleifera Lam., commonly known as the drumstick tree, is a highly nutritious medicinal plant belonging to the family Moringaceae. It has gained considerable scientific attention due to its rich nutritional composition and diverse pharmacological properties. Various parts of the plant, particularly the leaves, seeds, flowers and pods, contain essential vitamins, minerals, amino acids and several bioactive phytoconstituents, including flavonoids, phenolic compounds, alkaloids, glucosinolates, isothiocyanates and terpenoids. These phytochemicals contribute to its reported antioxidant, antidiabetic, anticancer, antiviral, anti-inflammatory and antihypertensive activities. Recent advancements in network pharmacology have provided valuable insights into the complex interactions between Moringa-derived phytochemicals and multiple molecular targets involved in disease pathways. Computational approaches such as molecular docking, target prediction and pathway enrichment analysis have helped identify potential mechanisms of action, particularly in insulin resistance, cancer and inflammatory disorders. This review highlights the nutritional significance, cultivation, processing methods, phytochemical composition and major pharmacological activities of Moringa oleifera, with particular emphasis on its molecular mechanisms and therapeutic potential. Although existing preclinical and computational findings are promising, further experimental validation and well-designed clinical studies are necessary to establish its safety, efficacy and clinical applications.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 16%
Moringa oleifera research and applications
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