Short-read whole-genome sequencing identifies the Tg(Tal1-cre/ERT)42-056Jrg transgene insertion site on mouse chromosome 4
Tg(Tal1-cre/ERT)42-056Jrg, also known as HSC-Scl-CreERT, is a well-used transgenic allele that enables genetic manipulation in mouse hematopoietic cells. Using short-read whole-genome sequencing, we identified the transgene insertion site on chromosome 4 approximately 6 kb upstream of Echdc2.
Authors
- Ross L. Levine (ORCID: https://orcid.org/0000-0002-7884-1905)
- Alexander G. Goglia (ORCID: https://orcid.org/0000-0003-3970-2694)
- Xiaodi Wu (ORCID: https://orcid.org/0000-0003-0886-8640)
- Pablo Sánchez Vela (ORCID: https://orcid.org/0000-0002-9286-8290)
- Maya C. Bagish
Institutions
- Memorial Sloan Kettering Cancer Center (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-11-05
- DOI
- https://doi.org/10.64898/2026.11.04.764251
- Primary Topic
- Animal Genetics and Reproduction
- Type
- preprint