A diagnostic stewardship initiative to improve diagnosis of norovirus and nitazoxanide utilization in patients with cancer
Patients and healthcare workers are at risk of norovirus infection. Nitazoxanide is often given, though data is lacking. Multiplex polymerase chain reaction platforms may yield false-positive results. A quality improvement initiative led to an 84.4% reduction in nitazoxanide utilization and substantial cost savings without compromising patient care or nosocomial infection.
Authors
- Guy H. Handley (ORCID: https://orcid.org/0000-0002-1678-5848)
- Amy Spallone (ORCID: https://orcid.org/0000-0002-7513-6522)
- Javier A. Adachi (ORCID: https://orcid.org/0000-0001-9721-8804)
- Amin Majid Alousi (ORCID: https://orcid.org/0000-0002-2498-8573)
- Nancy N Vuong (ORCID: https://orcid.org/0000-0002-3053-9897)
- Roy F. Chemaly (ORCID: https://orcid.org/0000-0002-0277-3088)
- Samuel A. Shelburne (ORCID: https://orcid.org/0000-0001-9721-263X)
- Micah M. Bhatti (ORCID: https://orcid.org/0000-0001-5857-5825)
- Jovan Borjan (ORCID: https://orcid.org/0000-0001-6323-6211)
- Sherry S. Cantu (ORCID: https://orcid.org/0009-0005-7618-3071)
- Patricia Munzy
- Ameera Munzy
- Alyssa Fluker (ORCID: https://orcid.org/0009-0009-3313-1879)
Institutions
- The University of Texas MD Anderson Cancer Center (US)
Publication Details
- Journal
- Infection Control and Hospital Epidemiology
- Published
- 2026-11-05
- DOI
- https://doi.org/10.1017/ice.2026.10605
- Primary Topic
- Viral gastroenteritis research and epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00