Prediction of elective surgical red blood cell transfusion reveals surgeon-level variation

BACKGROUND Preoperative prediction of red blood cell (RBC) transfusion in elective surgery serves two complementary purposes: enabling patient blood management (PBM) interventions before surgery and supporting blood product supply planning for elective lists. Beyond patient risk factors, individual surgeon practice may also contribute to transfusion rates, but this effect has not been fully quantified. STUDY DESIGN AND METHODS In a retrospective cohort of 279,905 elective surgical procedures at Helsinki University Hospital (2021-2025), we trained four gradient-boosted tree (CatBoost) models crossing patient factors with procedure group and pseudonymised surgeon identity. All predictors were restricted to data available seven or more days before scheduled surgery. The primary outcome was any allogeneic RBC transfusion from operating-room entry through seven postoperative days. Discrimination was assessed by the area under the precision-recall curve (AUPRC) on a held-out 20% test set. Surgeon-level effects were characterised by Shapley additive explanation (SHAP) values. RESULTS The transfusion rate was 2.2%. The patient-only model achieved AUPRC 0.261 (no-skill baseline 0.022). Adding surgeon identity to the procedure-adjusted model increased AUPRC from 0.440 to 0.472 (+0.032; 95% CI 0.020-0.044), raising lift from 20.3 to 21.7. Surgeon identity was the third most important of 72 features by permutation importance. DISCUSSION The operating surgeon was associated with RBC transfusion beyond patient and procedure factors, and surgeon identity was the third most important predictor in a deployment-realistic model using only data available a week before surgery. This information is readily available from routine records and could support PBM audit and blood supply planning for elective surgery.

Authors

Institutions

Publication Details

Journal
medRxiv
Published
2026-11-05
DOI
https://doi.org/10.64898/2026.11.03.26364952
Primary Topic
Blood transfusion and management
Type
preprint
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
NOV
preprint

Prediction of elective surgical red blood cell transfusion reveals surgeon-level variation

Minna Ilmakunnas, Esa V. Turkulainen, Mikko Arvas, Miika Koskinen
medRxiv
Blood transfusion and management
preprint

Prediction of elective surgical red blood cell transfusion reveals surgeon-level variation

Minna Ilmakunnas, Esa V. Turkulainen, Mikko Arvas, Miika Koskinen
preprint en

Abstract

BACKGROUND Preoperative prediction of red blood cell (RBC) transfusion in elective surgery serves two complementary purposes: enabling patient blood management (PBM) interventions before surgery and supporting blood product supply planning for elective lists. Beyond patient risk factors, individual surgeon practice may also contribute to transfusion rates, but this effect has not been fully quantified. STUDY DESIGN AND METHODS In a retrospective cohort of 279,905 elective surgical procedures at Helsinki University Hospital (2021-2025), we trained four gradient-boosted tree (CatBoost) models crossing patient factors with procedure group and pseudonymised surgeon identity. All predictors were restricted to data available seven or more days before scheduled surgery. The primary outcome was any allogeneic RBC transfusion from operating-room entry through seven postoperative days. Discrimination was assessed by the area under the precision-recall curve (AUPRC) on a held-out 20% test set. Surgeon-level effects were characterised by Shapley additive explanation (SHAP) values. RESULTS The transfusion rate was 2.2%. The patient-only model achieved AUPRC 0.261 (no-skill baseline 0.022). Adding surgeon identity to the procedure-adjusted model increased AUPRC from 0.440 to 0.472 (+0.032; 95% CI 0.020-0.044), raising lift from 20.3 to 21.7. Surgeon identity was the third most important of 72 features by permutation importance. DISCUSSION The operating surgeon was associated with RBC transfusion beyond patient and procedure factors, and surgeon identity was the third most important predictor in a deployment-realistic model using only data available a week before surgery. This information is readily available from routine records and could support PBM audit and blood supply planning for elective surgery.

medRxiv
Helsinki University Hospital (FI), Finnish Red Cross (FI), Hospital District of Helsinki and Uusimaa (FI)
Blood transfusion and management
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Laika access coming soon