Acute Pesticide Poisoning in Emergency Care: An Eight-Year Retrospective Analysis of Clinical Patterns and Outcomes

(1) Background: Pesticide poisoning is an inherent risk associated with the widespread use of pesticides in agriculture, and treatment largely depends on the type of pesticide involved. Thus, this retrospective study aimed to evaluate the clinical manifestation, symptoms associated, and treatment administered to patients with acute pesticide poisoning admitted to the Emergency Department of “Sf. Spiridon” Clinical Emergency Hospital in Iasi, Romania, and to investigate potential associations between pesticide type, clinical status and therapeutic management. (2) Methods: A sample of 46 patients presenting in the emergency unit with pesticide poisoning was assessed regarding clinical presentation and treatment received. (3) Results: Most poisoning cases were caused by insecticides (78.3%), followed by herbicides (21.7%). The predominant route of exposure was through ingestion (47.8%), followed by inhalation (21.7%). Gastrointestinal symptoms were the most frequent across all patients, while neurologic symptoms were frequent across the insecticide group. The median number of medications or procedures administered per patient was 3.0 in the insecticide group and 4.5 in the herbicide group. A non-significant trend toward more intensive treatment was observed in herbicide poisoning. Significant differences were found in the use of corticosteroids and calcium, with higher usage among herbicide patients. (4) Conclusions: These results reflect the heterogeneity of the clinical presentation depending on the pesticide, showcasing the need for individualised therapeutic approaches.

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Journal
Journal of Xenobiotics
Published
2026-11-05
DOI
https://doi.org/10.3390/jox16070217
Primary Topic
Poisoning and overdose treatments
Type
article
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article

Acute Pesticide Poisoning in Emergency Care: An Eight-Year Retrospective Analysis of Clinical Patterns and Outcomes

Diana Carmen Cimpoesu, Luminiţa Agoroaei, Viorica Popa, Paul Lucian Nedelea et al.
Journal of Xenobiotics
Poisoning and overdose treatments
article

Acute Pesticide Poisoning in Emergency Care: An Eight-Year Retrospective Analysis of Clinical Patterns and Outcomes

Diana Carmen Cimpoesu, Luminiţa Agoroaei, Viorica Popa, Paul Lucian Nedelea, Ioana-Cezara Caba, Roxana Elena Ciuntu, Ivona Mitu, Mihaela Corlade-Andrei, Alina Delia Popa, Andreea-Maria Mitran, Alexandra Haută, Mihai-Vlad Herțescu
article en

Abstract

(1) Background: Pesticide poisoning is an inherent risk associated with the widespread use of pesticides in agriculture, and treatment largely depends on the type of pesticide involved. Thus, this retrospective study aimed to evaluate the clinical manifestation, symptoms associated, and treatment administered to patients with acute pesticide poisoning admitted to the Emergency Department of “Sf. Spiridon” Clinical Emergency Hospital in Iasi, Romania, and to investigate potential associations between pesticide type, clinical status and therapeutic management. (2) Methods: A sample of 46 patients presenting in the emergency unit with pesticide poisoning was assessed regarding clinical presentation and treatment received. (3) Results: Most poisoning cases were caused by insecticides (78.3%), followed by herbicides (21.7%). The predominant route of exposure was through ingestion (47.8%), followed by inhalation (21.7%). Gastrointestinal symptoms were the most frequent across all patients, while neurologic symptoms were frequent across the insecticide group. The median number of medications or procedures administered per patient was 3.0 in the insecticide group and 4.5 in the herbicide group. A non-significant trend toward more intensive treatment was observed in herbicide poisoning. Significant differences were found in the use of corticosteroids and calcium, with higher usage among herbicide patients. (4) Conclusions: These results reflect the heterogeneity of the clinical presentation depending on the pesticide, showcasing the need for individualised therapeutic approaches.

Journal of XenobioticsVol. 16(7)
Grigore T. Popa University of Medicine and Pharmacy (RO), Spitalul Clinic Judeţean de Urgenţe "Sf. Spiridon" Iaşi (RO)
Openalex Percentile: Top 11%
Poisoning and overdose treatments
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