Should the dose of atorvastatin 80mg be lowered when combined with ezetimibe 10mg in an 82-year-old female with stage 4 CKD and atrial fibrillation?

Direct evidence suggests caution with high-dose atorvastatin in elderly patients with CKD; reducing the dose when combined with ezetimibe might mitigate myopathy risk. Close monitoring and shared decision-making are advised.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-11-05
DOI
https://doi.org/10.5281/zenodo.23970781
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Should the dose of atorvastatin 80mg be lowered when combined with ezetimibe 10mg in an 82-year-old female with stage 4 CKD and atrial fibrillation?

Tripdatabase
Zenodo (CERN European Organization for Nuclear Research)
Lipoproteins and Cardiovascular Health
article

Should the dose of atorvastatin 80mg be lowered when combined with ezetimibe 10mg in an 82-year-old female with stage 4 CKD and atrial fibrillation?

Tripdatabase
article en

Abstract

Direct evidence suggests caution with high-dose atorvastatin in elderly patients with CKD; reducing the dose when combined with ezetimibe might mitigate myopathy risk. Close monitoring and shared decision-making are advised.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 12%
Lipoproteins and Cardiovascular Health
DOIOpen Access PDFOpenAlex
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Should the dose of atorvastatin 80mg be lowered when combined with ezetimibe 10mg in an 82-year-old female with stage 4 CKD and atrial fibrillation? — Tripdatabase · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS