MDNA is a hematopoietic system-specific interferon stimulated gene.
We demonstrate here selective control of the interferon-stimulated gene (ISG) MDNA in the hematopoietic compartment. MDNA was induced in cells of the blood following interferon pathway activation by IFN-alpha or following interferon pathway activation associated with viral infection. In human cells l, MDNA expression was controlled at least in part by the NLR receptor NOD2.
Authors
- Shahan Mamoor (ORCID: https://orcid.org/0000-0003-4150-0936)
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2026-11-05
- DOI
- https://doi.org/10.5281/zenodo.23978413
- Primary Topic
- interferon and immune responses
- Type
- preprint