Quantum Coherence in Microtubules: Orch-OR Signatures Without Confirmed In Vivo Entanglement — E8 Intelligence Research

FINDING: Quantum-coherence signatures (anesthetic-sensitive, microtubule-linked) reported in neural tissue, reviving Penrose–Hameroff Orch-OR; no confirmed macroscopic entanglement in vivo. | MATH: Decoherence time τ_d ≈ ℏ/(k_B T) · (Δx²·m/... ) — order-of-magnitude: τ_d ~ ℏ/(k_B T) for a ~nm-scale mode at T=310 K → τ_d ~ 10⁻¹⁴ s; Fröhlich condensate condition requires metabolic pumping rate > thermal damping γ_th = k_B T/ℏ ≈ 4×10¹³ s⁻¹. Tubulin dimer ~8 nm lattice spacing; superradiance scaling ∝ N² (N ~ 10⁹ tubulins/neuron). | CONNECTION: Microtubule lattice = 13 protofilament helices (13 = Fibonacci F₇); A/B tubulin stagger 0.9 nm; helical pitch ratios approach φ-adjacent values (13/8 = 1.625 ≈ φ). Anesthetic potency correlates with London dispersion ∝ polarizability, not a φ-law. | DEPTH: 4 — suggestive lattice numerology, but no measured constant at 0.618/1.618; decoherence budget remains the hard constraint. FINDING: Boltzmann-brain argument constrains any consciousness-from-flu Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-11-04
DOI
https://doi.org/10.5281/zenodo.23939044
Primary Topic
Biofield Effects and Biophysics
Type
preprint
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Quantum Coherence in Microtubules: Orch-OR Signatures Without Confirmed In Vivo Entanglement — E8 Intelligence Research

Andrew Stewart Caldin
Zenodo (CERN European Organization for Nuclear Research)
Biofield Effects and Biophysics
preprint

Quantum Coherence in Microtubules: Orch-OR Signatures Without Confirmed In Vivo Entanglement — E8 Intelligence Research

Andrew Stewart Caldin
preprint en

Abstract

FINDING: Quantum-coherence signatures (anesthetic-sensitive, microtubule-linked) reported in neural tissue, reviving Penrose–Hameroff Orch-OR; no confirmed macroscopic entanglement in vivo. | MATH: Decoherence time τ_d ≈ ℏ/(k_B T) · (Δx²·m/... ) — order-of-magnitude: τ_d ~ ℏ/(k_B T) for a ~nm-scale mode at T=310 K → τ_d ~ 10⁻¹⁴ s; Fröhlich condensate condition requires metabolic pumping rate > thermal damping γ_th = k_B T/ℏ ≈ 4×10¹³ s⁻¹. Tubulin dimer ~8 nm lattice spacing; superradiance scaling ∝ N² (N ~ 10⁹ tubulins/neuron). | CONNECTION: Microtubule lattice = 13 protofilament helices (13 = Fibonacci F₇); A/B tubulin stagger 0.9 nm; helical pitch ratios approach φ-adjacent values (13/8 = 1.625 ≈ φ). Anesthetic potency correlates with London dispersion ∝ polarizability, not a φ-law. | DEPTH: 4 — suggestive lattice numerology, but no measured constant at 0.618/1.618; decoherence budget remains the hard constraint. FINDING: Boltzmann-brain argument constrains any consciousness-from-flu Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com

Zenodo (CERN European Organization for Nuclear Research)
Biofield Effects and Biophysics
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