Nickel-Catalyzed N -Arylation of NH -Sulfoximines via Direct Visible-Light Excitation

Abstract Sulfoximines are versatile motifs in synthetic and medicinal chemistry. Herein, we report a visible-light-induced nickel-catalyzed N-arylation of NH-sulfoximines with aryl chlorides and (hetero)aryl bromides under mild conditions without an exogenous photocatalyst. The reaction exhibits broad functional-group tolerance, accommodates structurally diverse sulfoximines, and enables the late-stage functionalization of pharmaceutically relevant molecules.