Severe Orofacial Cryogenic Injury Requiring Tracheostomy Due to Recreational Nitrous Oxide Inhalation

Abstract Recreational use of nitrous oxide (N 2 O) has become more popular recently due to its euphoric effect as well as viral social media trends. Nitrous oxide use can cause severe frostbite injuries at any site of direct contact with the gas or canister, including the face, oral cavity, and oropharynx. We present a case of severe orofacial cryogenic injury from commercially available nitrous oxide marketed as Galaxy Gas resulting in prolonged tracheostomy dependence.