Effects of low-dose cervical paraspinal lidocaine injections on cervicogenic dizziness–related outcomes: a randomized, sham-controlled, assessor-blinded trial

PURPOSE: To determine whether low-dose cervical paraspinal intramuscular lidocaine injections improve dizziness-related disability and cervical sensorimotor outcomes in cervicogenic dizziness. MATERIALS AND METHODS: = 40) twice weekly for five weeks (10 sessions). The primary endpoint was change in Dizziness Handicap Inventory (DHI) total score. Secondary outcomes included DHI subscales, Neck Disability Index, neck pain, cervical range of motion, joint position error, posturography, kinesiophobia, anxiety, and depression. Analyses used intention-to-treat linear mixed-effects models. RESULTS: | 0.30-1.13). Adverse events were infrequent and mostly mild. CONCLUSIONS: Lidocaine injections produced a modest short-term improvement in dizziness-related disability. Without verified participant blinding, long-term follow-up, or testing alongside rehabilitation, these findings require confirmation.

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Publication Details

Journal
Disability and Rehabilitation
Published
2026-11-04
DOI
https://doi.org/10.1080/09638288.2026.2758275
Primary Topic
Vestibular and auditory disorders
Type
article
Field-Weighted Citation Impact
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article

Effects of low-dose cervical paraspinal lidocaine injections on cervicogenic dizziness–related outcomes: a randomized, sham-controlled, assessor-blinded trial

Riccardo Xavier Micarelli, Andrea Viziano, Willem De Hertogh, Alessandro Micarelli et al.
Disability and Rehabilitation
Vestibular and auditory disorders
article

Effects of low-dose cervical paraspinal lidocaine injections on cervicogenic dizziness–related outcomes: a randomized, sham-controlled, assessor-blinded trial

Riccardo Xavier Micarelli, Andrea Viziano, Willem De Hertogh, Alessandro Micarelli, A Di Benedetto, Emanuele Gregorace, Ivan Granito, Marco Alessandrini, Cesare MATERAZZETTI
article en

Abstract

PURPOSE: To determine whether low-dose cervical paraspinal intramuscular lidocaine injections improve dizziness-related disability and cervical sensorimotor outcomes in cervicogenic dizziness. MATERIALS AND METHODS: = 40) twice weekly for five weeks (10 sessions). The primary endpoint was change in Dizziness Handicap Inventory (DHI) total score. Secondary outcomes included DHI subscales, Neck Disability Index, neck pain, cervical range of motion, joint position error, posturography, kinesiophobia, anxiety, and depression. Analyses used intention-to-treat linear mixed-effects models. RESULTS: | 0.30-1.13). Adverse events were infrequent and mostly mild. CONCLUSIONS: Lidocaine injections produced a modest short-term improvement in dizziness-related disability. Without verified participant blinding, long-term follow-up, or testing alongside rehabilitation, these findings require confirmation.

Disability and Rehabilitation
University of Rome Tor Vergata (IT), University of Antwerp (BE), Fondazione Santa Lucia (IT)
Openalex Percentile: Top 19%
Vestibular and auditory disorders
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