Effects of low-dose cervical paraspinal lidocaine injections on cervicogenic dizziness–related outcomes: a randomized, sham-controlled, assessor-blinded trial
PURPOSE: To determine whether low-dose cervical paraspinal intramuscular lidocaine injections improve dizziness-related disability and cervical sensorimotor outcomes in cervicogenic dizziness. MATERIALS AND METHODS: = 40) twice weekly for five weeks (10 sessions). The primary endpoint was change in Dizziness Handicap Inventory (DHI) total score. Secondary outcomes included DHI subscales, Neck Disability Index, neck pain, cervical range of motion, joint position error, posturography, kinesiophobia, anxiety, and depression. Analyses used intention-to-treat linear mixed-effects models. RESULTS: | 0.30-1.13). Adverse events were infrequent and mostly mild. CONCLUSIONS: Lidocaine injections produced a modest short-term improvement in dizziness-related disability. Without verified participant blinding, long-term follow-up, or testing alongside rehabilitation, these findings require confirmation.
Authors
- Riccardo Xavier Micarelli
- Andrea Viziano (ORCID: https://orcid.org/0000-0002-6413-1785)
- Willem De Hertogh (ORCID: https://orcid.org/0000-0001-8856-2507)
- Alessandro Micarelli (ORCID: https://orcid.org/0000-0002-0495-5272)
- A Di Benedetto
- Emanuele Gregorace
- Ivan Granito
- Marco Alessandrini (ORCID: https://orcid.org/0000-0001-9955-6890)
- Cesare MATERAZZETTI
Institutions
- University of Rome Tor Vergata (IT)
- University of Antwerp (BE)
- Fondazione Santa Lucia (IT)
Publication Details
- Journal
- Disability and Rehabilitation
- Published
- 2026-11-04
- DOI
- https://doi.org/10.1080/09638288.2026.2758275
- Primary Topic
- Vestibular and auditory disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00