Comparative Evaluation of Transdermal Diclofenac Patch Versus Oral Diclofenac Sodium for Postoperative Pain Management Following Normal Extraction: A Clinical Prospective Original Study

Effective postoperative pain control is very important in any kind of surgery. Diclofenac sodium, a common non steroid anti-inflammatory drug (NSAID), is easily available in various formulations, including oral and transdermal. This study compares the tolerability, efficacy in a peptic ulcer, gastro esophageal reflux diseases (GERD) and upper gastrointestinal diseases patients and adverse effects of transdermal versus oral diclofenac sodium in managing postoperative pain after normal extractions. Methods: A clinical study was conducted on 200 patients undergoing teeth extractions, divided into two groups (n=100 each). Group A received 200 mg transdermal diclofenac patches (once daily for 3 days), and Group B received 100 mg oral diclofenac tablets (twice daily for 3 days). Pain relief was evaluated using a 4-point pain relief score scale on postoperative days 1, 2, and 3. Tolerability, adverse effects, and patient comfort were also assessed. Results: Group A showed significantly higher mean pain relief scores on all three days compared to Group B (p<0.05). Group A had fewer adverse effects, with 90% reporting no complications, compared to 50% in Group B (p=0.0002). Tolerability and patient comfort were significantly better in Group A (p=0.0190 and p=0.0030, respectively). Conclusion: Transdermal diclofenac patches create effective and well-tolerated postoperative pain relief with fewer side effects and better patient compliance than oral diclofenac. They present a viable alternative for postoperative analgesia in regularly practiced oral surgery.

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Publication Details

Journal
Journal of chemical health risks
Published
2026-11-02
Primary Topic
Anesthesia and Pain Management
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article
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article

Comparative Evaluation of Transdermal Diclofenac Patch Versus Oral Diclofenac Sodium for Postoperative Pain Management Following Normal Extraction: A Clinical Prospective Original Study

Md. Tipu Sultan
Journal of chemical health risks
Anesthesia and Pain Management
article

Comparative Evaluation of Transdermal Diclofenac Patch Versus Oral Diclofenac Sodium for Postoperative Pain Management Following Normal Extraction: A Clinical Prospective Original Study

Md. Tipu Sultan
article en

Abstract

Effective postoperative pain control is very important in any kind of surgery. Diclofenac sodium, a common non steroid anti-inflammatory drug (NSAID), is easily available in various formulations, including oral and transdermal. This study compares the tolerability, efficacy in a peptic ulcer, gastro esophageal reflux diseases (GERD) and upper gastrointestinal diseases patients and adverse effects of transdermal versus oral diclofenac sodium in managing postoperative pain after normal extractions. Methods: A clinical study was conducted on 200 patients undergoing teeth extractions, divided into two groups (n=100 each). Group A received 200 mg transdermal diclofenac patches (once daily for 3 days), and Group B received 100 mg oral diclofenac tablets (twice daily for 3 days). Pain relief was evaluated using a 4-point pain relief score scale on postoperative days 1, 2, and 3. Tolerability, adverse effects, and patient comfort were also assessed. Results: Group A showed significantly higher mean pain relief scores on all three days compared to Group B (p<0.05). Group A had fewer adverse effects, with 90% reporting no complications, compared to 50% in Group B (p=0.0002). Tolerability and patient comfort were significantly better in Group A (p=0.0190 and p=0.0030, respectively). Conclusion: Transdermal diclofenac patches create effective and well-tolerated postoperative pain relief with fewer side effects and better patient compliance than oral diclofenac. They present a viable alternative for postoperative analgesia in regularly practiced oral surgery.

Journal of chemical health risks
Openalex Percentile: Top 10%
Anesthesia and Pain Management
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