Mechanistic Evidence and the Challenge of Mechanism Individuation

Abstract Randomized controlled trials (RCTs) are widely employed to inform policy decisions in the social and behavioral sciences. Yet both philosophers and scientists have questioned the reliability of effect-size evidence derived from RCTs for policy extrapolation, arguing that RCT findings should be complemented by evidence about the mechanism through which a policy works. We agree that mechanisms are important but argue that existing accounts face the challenge of mechanism individuation . In this article, we explain what the challenge consists in, focusing on common practices of policy scaling-up, transferring policy to new domains, and aggregating policy-relevant evidence.

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Publication Details

Journal
Philosophy of Science
Published
2026-11-03
DOI
https://doi.org/10.1017/psa.2026.10289
Primary Topic
Philosophy and History of Science
Type
article
Field-Weighted Citation Impact
0.00
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article

Mechanistic Evidence and the Challenge of Mechanism Individuation

Caterina Marchionni, Till Grüne‐Yanoff
Philosophy of Science
Philosophy and History of Science
article

Mechanistic Evidence and the Challenge of Mechanism Individuation

Caterina Marchionni, Till Grüne‐Yanoff
article en

Abstract

Abstract Randomized controlled trials (RCTs) are widely employed to inform policy decisions in the social and behavioral sciences. Yet both philosophers and scientists have questioned the reliability of effect-size evidence derived from RCTs for policy extrapolation, arguing that RCT findings should be complemented by evidence about the mechanism through which a policy works. We agree that mechanisms are important but argue that existing accounts face the challenge of mechanism individuation . In this article, we explain what the challenge consists in, focusing on common practices of policy scaling-up, transferring policy to new domains, and aggregating policy-relevant evidence.

Philosophy of Science
University of Helsinki (FI), KTH Royal Institute of Technology (SE)
Openalex Percentile: Top 5%
Philosophy and History of Science
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