Latex Allergy Presenting with Allergic Rhinoconjunctivitis and Asthma in a Theatre Nurse: A Case Report

Abstract Introduction: Natural rubber latex (NRL) allergy is a significant occupational hazard among healthcare workers, driven largely by airborne latex proteins bound to glove powder. Continued workplace exposure can lead to upper and lower airway sensitization, presenting as occupational allergic rhinoconjunctivitis and asthma. Case Report: A 29-year-old female theatre nurse presented with a six-year history of workplace-related shortness of breath, wheezing, cough, and ocular-nasal symptoms triggered by powdered latex gloves. Laboratory findings were unremarkable, but skin prick testing was positive for latex (5 × 6𝑚𝑚 wheal). Spirometry demonstrated variable airflow limitation with significant bronchodilator responsiveness (12.2% and 220 mL improvement in 𝐹𝐸𝑉1), supporting a diagnosis of occupational asthma and allergic rhinoconjunctivitis. Symptoms were managed with inhaled therapy and complete avoidance of latex gloves using nitrile alternatives. Conclusion: Early clinical recognition, detailed exposure history, objective allergy and pulmonary testing, and prompt substitution with non-latex alternatives are critical in managing occupational latex allergy in healthcare settings.