Sildenafil as a Diagnostic Tool and Treatment Option for Popliteal Artery Entrapment Syndrome: A Case Report

ABSTRACT: Popliteal artery entrapment syndrome (PAES) is characterized by activity-related, lower extremity claudication symptoms including exertional calf pain, weakness, cramping, foot paresthesia, and reports of increased calf tension. Diagnosis can be challenging and has overlap with other lower extremity exertional conditions. This case report describes a case of a 21-year-old female athlete presenting with progressive exertional bilateral calf pain during tennis matches recalcitrant to numerous treatment options. A course of sildenafil was noted to provide symptomatic relief and allowed the athlete to participate near pain free temporarily. Her symptoms worsened despite continued sildenafil use with exercise and required surgical intervention. Sildenafil may be a useful diagnostic option in the workup for PAES.

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Publication Details

Journal
Clinical Journal of Sport Medicine
Published
2026-11-03
DOI
https://doi.org/10.1097/jsm.0000000000001525
Primary Topic
Vascular anomalies and interventions
Type
article
Field-Weighted Citation Impact
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article

Sildenafil as a Diagnostic Tool and Treatment Option for Popliteal Artery Entrapment Syndrome: A Case Report

Daniel M. Cushman, Armaghan M. Mardashti, Branden I. Middleton
Clinical Journal of Sport Medicine
Vascular anomalies and interventions
article

Sildenafil as a Diagnostic Tool and Treatment Option for Popliteal Artery Entrapment Syndrome: A Case Report

Daniel M. Cushman, Armaghan M. Mardashti, Branden I. Middleton
article en

Abstract

ABSTRACT: Popliteal artery entrapment syndrome (PAES) is characterized by activity-related, lower extremity claudication symptoms including exertional calf pain, weakness, cramping, foot paresthesia, and reports of increased calf tension. Diagnosis can be challenging and has overlap with other lower extremity exertional conditions. This case report describes a case of a 21-year-old female athlete presenting with progressive exertional bilateral calf pain during tennis matches recalcitrant to numerous treatment options. A course of sildenafil was noted to provide symptomatic relief and allowed the athlete to participate near pain free temporarily. Her symptoms worsened despite continued sildenafil use with exercise and required surgical intervention. Sildenafil may be a useful diagnostic option in the workup for PAES.

Clinical Journal of Sport Medicine
Howard University (US), University of Utah (US)
Openalex Percentile: Top 11%
Vascular anomalies and interventions
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Sildenafil as a Diagnostic Tool and Treatment Option for Popliteal Artery Entrapment Syndrome: A Case Report — Daniel M. Cushman, Armaghan M. Mardashti, et al. · Clinical Journal of Sport Medicine (2026) | TGRS Research Map | TGRS