Comparative Study of Regional Versus General Anaesthesia for Common Surgical Procedures: A Multi-Centre Experience from Tertiary Care Hospitals in Pakistan

Objective: To compare perioperative outcomes, complication rates and satisfaction of surgeries with regional anaesthesia (RA) and general anaesthesia (GA) in patients undergoing common surgeries in tertiary care hospitals of Pakistan. Study Design: Comparative Cross-sectional study. Place & Duration of Study: Departments of Anaesthesiology in three tertiary care hospitals in Pakistan from October 2025 to March 2026. Methodology: A total of 110 patients who were able to give informed consent and were aged ≥ 18 years for elective common surgical procedures were enrolled and randomly divided into two groups: regional anaesthesia (RA; n=55) and general anaesthesia (GA; n=55). Intraoperative hypotension, visual analogue scale (VAS) pain score, PACU stay, and time to mobilisation, analgesic requirements, complications, and satisfaction scores were collected that allowed for a comparison of peri-operative parameters. The data were analyzed using SPSS version 26.0. Results: The complication rate was significantly lower for the RA group than for GA (45.5% vs 76.4%; p<0.001). RA was associated with significantly lower VAS pain scores (4.2 ± 1.3 vs 7.6 ± 1.8; p<0.001), shorter PACU stay (1.4 ± 0.6 vs 2.6 ± 0.9 hours; p<0.001), earlier mobilisation (3.2 ± 1.1 vs 5.9 ± 1.7 hours; p<0.001), reduced analgesic requirements, and higher patient satisfaction scores (4.3 ± 0.6 vs 3.5 ± 0.8; p<0.001). PONV was significantly higher in GA group vs RA group (32.7% vs 10.9%; p=0.006). Conclusion: Regional anaesthesia has better peri-operative outcomes, less complication rates and better satisfaction with care for common surgical procedures when compared to general anaesthesia. In resource-limited environments, and when clinically indicated, RA should be the preferred anaesthetic technique.

Authors

Institutions

Publication Details

Journal
International Journal of Drug Delivery Technology
Published
2026-11-03
DOI
https://doi.org/10.25258/ijddt.16.86s.86
Primary Topic
Anesthesia and Pain Management
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Comparative Study of Regional Versus General Anaesthesia for Common Surgical Procedures: A Multi-Centre Experience from Tertiary Care Hospitals in Pakistan

Shahneela Raza, Ayesha Fatima, Erum Naz, Amna Khan et al.
International Journal of Drug Delivery Technology
Anesthesia and Pain Management
article

Comparative Study of Regional Versus General Anaesthesia for Common Surgical Procedures: A Multi-Centre Experience from Tertiary Care Hospitals in Pakistan

Shahneela Raza, Ayesha Fatima, Erum Naz, Amna Khan, Sara Khan, Muhammad Javed Khan
article en

Abstract

Objective: To compare perioperative outcomes, complication rates and satisfaction of surgeries with regional anaesthesia (RA) and general anaesthesia (GA) in patients undergoing common surgeries in tertiary care hospitals of Pakistan. Study Design: Comparative Cross-sectional study. Place & Duration of Study: Departments of Anaesthesiology in three tertiary care hospitals in Pakistan from October 2025 to March 2026. Methodology: A total of 110 patients who were able to give informed consent and were aged ≥ 18 years for elective common surgical procedures were enrolled and randomly divided into two groups: regional anaesthesia (RA; n=55) and general anaesthesia (GA; n=55). Intraoperative hypotension, visual analogue scale (VAS) pain score, PACU stay, and time to mobilisation, analgesic requirements, complications, and satisfaction scores were collected that allowed for a comparison of peri-operative parameters. The data were analyzed using SPSS version 26.0. Results: The complication rate was significantly lower for the RA group than for GA (45.5% vs 76.4%; p<0.001). RA was associated with significantly lower VAS pain scores (4.2 ± 1.3 vs 7.6 ± 1.8; p<0.001), shorter PACU stay (1.4 ± 0.6 vs 2.6 ± 0.9 hours; p<0.001), earlier mobilisation (3.2 ± 1.1 vs 5.9 ± 1.7 hours; p<0.001), reduced analgesic requirements, and higher patient satisfaction scores (4.3 ± 0.6 vs 3.5 ± 0.8; p<0.001). PONV was significantly higher in GA group vs RA group (32.7% vs 10.9%; p=0.006). Conclusion: Regional anaesthesia has better peri-operative outcomes, less complication rates and better satisfaction with care for common surgical procedures when compared to general anaesthesia. In resource-limited environments, and when clinically indicated, RA should be the preferred anaesthetic technique.

International Journal of Drug Delivery TechnologyVol. 16(86s)
Jinnah Postgraduate Medical Center (PK), Khyber Teaching Hospital (PK), Civil Hospital Karachi (PK), Sindh Institute of Urology and Transplantation (PK), Bahria University (PK)
Openalex Percentile: Top 11%
Anesthesia and Pain Management
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Laika access coming soon