Safety Assessment of Hydroxyacetophenone as Used in Cosmetics

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Hydroxyacetophenone as used in cosmetic formulations. This ingredient is reported to function in cosmetics as an antioxidant and skin-conditioning agent. The Panel reviewed relevant data related to the safety of this ingredient in cosmetic formulations, and concluded that Hydroxyacetophenone is safe in cosmetics in the present practices of use and concentration described in this safety assessment.

Authors

Publication Details

Journal
International Journal of Toxicology
Published
2026-11-02
DOI
https://doi.org/10.1177/10915818261497291
Primary Topic
Contact Dermatitis and Allergies
Type
article
Field-Weighted Citation Impact
0.00
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article

Safety Assessment of Hydroxyacetophenone as Used in Cosmetics

Paul W. Snyder, Monice M. Fiume, David Ross, Preethi S. Raj et al.
International Journal of Toxicology
Contact Dermatitis and Allergies
article

Safety Assessment of Hydroxyacetophenone as Used in Cosmetics

Paul W. Snyder, Monice M. Fiume, David Ross, Preethi S. Raj, Ronald C. Shank, Allan E. Rettie, Daniel C. Liebler, Bart A. Heldreth, Thomas J. Slaga, Wilma Fowler Bergfeld, Curtis D. Klaassen, Susan C. Tilton, David E. Cohen, Donald V. Belsito
article en

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Hydroxyacetophenone as used in cosmetic formulations. This ingredient is reported to function in cosmetics as an antioxidant and skin-conditioning agent. The Panel reviewed relevant data related to the safety of this ingredient in cosmetic formulations, and concluded that Hydroxyacetophenone is safe in cosmetics in the present practices of use and concentration described in this safety assessment.

International Journal of Toxicology
Openalex Percentile: Top 11%
Contact Dermatitis and Allergies
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