ACID–BASE REACTION-BASED ORALLY DISINTEGRATING TABLETS: FORMULATION STRATEGIES, MECHANISMS, EVALUATION, AND RECENT ADVANCES

Oral administration of drugs is preferred due to its ease of swallowing, distress avoidance, versatility and most significantly, patient compliance. The large number of patients find it difficult to swallow tablets and capsules, and do not take their medicines as prescribed. The most evident drawback of the commonly used oral dosage forms like tablets and capsules is difficulty in swallowing leading to patient’s incompliance particularly in case of Pediatric and geriatric patients.