Value of Magnetic Resonance Imaging in Evaluating the Outcomes of Transarterial Chemoembolization for Hepatocellular Carcinoma at E Hospital

Abstract: A retrospective study of 32 patients with primary liver cancer treated with transarterial chemoembolization (TACE) who underwent 1.5 Tesla magnetic resonance imaging (MRI) before and 1 month after intervention at E Hospital from May 2026 to October 2026 showed the following results: the mean age was 69.66 ± 8.31 years; 93.8% were male. A history of viral hepatitis was reported in 78.1% of patients, and cirrhosis in 53.1%. One month post-TACE, the median AFP level decreased from 9.70 ng/mL to 6.56 ng/mL; median bilirubin decreased from 11.85 µmol/L to 10.70 µmol/L. The median diameter of enhancing tumor tissue decreased from 35 mm to 21 mm. Dynamic MRI detected tumor enhancement in 56.2% of cases, while subtracted MRI detected true arterial enhancement in 78.1% of cases. According to mRECIST criteria, complete response (CR) was achieved in 21.9%, partial response (PR) in 46.9%, stable disease (SD) in 25.0%, and progressive disease (PD) in 6.3% (objective response rate of 68.8%). Compared with DSA, subtracted MRI achieved a sensitivity of 100%, specificity of 77.8%, accuracy of 93.8%, and a Kappa agreement coefficient of 0.834. Keywords: Hepatocellular carcinoma, TACE, dynamic subtraction MRI, mRECIST.

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Publication Details

Journal
VNU Journal of Science Medical and Pharmaceutical Sciences
Published
2026-11-03
DOI
https://doi.org/10.25073/2588-1132/vnumps.5148
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
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article

Value of Magnetic Resonance Imaging in Evaluating the Outcomes of Transarterial Chemoembolization for Hepatocellular Carcinoma at E Hospital

NGUYEN Dinh Phi, Nguyen Van Son
VNU Journal of Science Medical and Pharmaceutical Sciences
Hepatocellular Carcinoma Treatment and Prognosis
article

Value of Magnetic Resonance Imaging in Evaluating the Outcomes of Transarterial Chemoembolization for Hepatocellular Carcinoma at E Hospital

NGUYEN Dinh Phi, Nguyen Van Son
article en

Abstract

Abstract: A retrospective study of 32 patients with primary liver cancer treated with transarterial chemoembolization (TACE) who underwent 1.5 Tesla magnetic resonance imaging (MRI) before and 1 month after intervention at E Hospital from May 2026 to October 2026 showed the following results: the mean age was 69.66 ± 8.31 years; 93.8% were male. A history of viral hepatitis was reported in 78.1% of patients, and cirrhosis in 53.1%. One month post-TACE, the median AFP level decreased from 9.70 ng/mL to 6.56 ng/mL; median bilirubin decreased from 11.85 µmol/L to 10.70 µmol/L. The median diameter of enhancing tumor tissue decreased from 35 mm to 21 mm. Dynamic MRI detected tumor enhancement in 56.2% of cases, while subtracted MRI detected true arterial enhancement in 78.1% of cases. According to mRECIST criteria, complete response (CR) was achieved in 21.9%, partial response (PR) in 46.9%, stable disease (SD) in 25.0%, and progressive disease (PD) in 6.3% (objective response rate of 68.8%). Compared with DSA, subtracted MRI achieved a sensitivity of 100%, specificity of 77.8%, accuracy of 93.8%, and a Kappa agreement coefficient of 0.834. Keywords: Hepatocellular carcinoma, TACE, dynamic subtraction MRI, mRECIST.

VNU Journal of Science Medical and Pharmaceutical Sciences
Openalex Percentile: Top 15%
Hepatocellular Carcinoma Treatment and Prognosis
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Value of Magnetic Resonance Imaging in Evaluating the Outcomes of Transarterial Chemoembolization for Hepatocellular Carcinoma at E Hospital — NGUYEN Dinh Phi, Nguyen Van Son · VNU Journal of Science Medical and Pharmaceutical Sciences (2026) | TGRS Research Map | TGRS