Milk‐Derived Signals Guide Neonatal Hematopoiesis and Respiratory Defense

This commentary summarises a recent paper in Cell by Howard et al. showing that osteopontin shapes the infant microbiome, which in turn directs early immune development in the airways. This early programming confers protection against respiratory tract infections that persists well beyond infancy.

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Publication Details

Journal
Immunology and Cell Biology
Published
2026-11-02
DOI
https://doi.org/10.1111/imcb.70175
Primary Topic
Infant Nutrition and Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Milk‐Derived Signals Guide Neonatal Hematopoiesis and Respiratory Defense

Jonatan Leffler, Valérie Verhasselt, Nivedithaa Divakara
Immunology and Cell Biology
Infant Nutrition and Health
article

Milk‐Derived Signals Guide Neonatal Hematopoiesis and Respiratory Defense

Jonatan Leffler, Valérie Verhasselt, Nivedithaa Divakara
article en

Abstract

This commentary summarises a recent paper in Cell by Howard et al. showing that osteopontin shapes the infant microbiome, which in turn directs early immune development in the airways. This early programming confers protection against respiratory tract infections that persists well beyond infancy.

Immunology and Cell Biology
The Kids Research Institute Australia (AU), The University of Western Australia (AU)
Openalex Percentile: Top 15%
Infant Nutrition and Health
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