Activation of Xist by DNMT1 proceeds through FIRRE.

We provide evidence here for the existence of an alternative pathway for activation of Xist that proceeds through the non-coding RNA FIRRE following activation, mutation or loss of function of the DNA methyltransferase Dnmt1.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-11-03
DOI
https://doi.org/10.5281/zenodo.23929548
Primary Topic
Epigenetics and DNA Methylation
Type
preprint
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preprint

Activation of Xist by DNMT1 proceeds through FIRRE.

Shahan Mamoor
Zenodo (CERN European Organization for Nuclear Research)
Epigenetics and DNA Methylation
preprint

Activation of Xist by DNMT1 proceeds through FIRRE.

Shahan Mamoor
preprint en

Abstract

We provide evidence here for the existence of an alternative pathway for activation of Xist that proceeds through the non-coding RNA FIRRE following activation, mutation or loss of function of the DNA methyltransferase Dnmt1.

Zenodo (CERN European Organization for Nuclear Research)
Epigenetics and DNA Methylation
DOIOpen Access PDFOpenAlex
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Activation of Xist by DNMT1 proceeds through FIRRE. — Shahan Mamoor · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS