Number of Liver Metastases Stratifies Prognosis in Synchronous Metastatic Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy, frequently diagnosed at an advanced stage. While systemic chemotherapy is the standard of care for metastatic disease, clinical outcomes vary considerably among patients. Oligo-recurrence, limited metachronous metastasis potentially suitable for aggressive local treatment, has emerged as a clinically relevant concept associated with prolonged survival in selected patients, while the prognostic significance of synchronous oligometastasis, limited metastatic disease present at initial diagnosis, remains poorly characterized in PDAC.
Authors
- Yuto Yamahata (ORCID: https://orcid.org/0009-0007-5716-2480)
- Masashi Tsunematsu (ORCID: https://orcid.org/0000-0001-6953-1801)
- Kenei Furukawa (ORCID: https://orcid.org/0000-0002-5081-6417)
- Ryoga Hamura (ORCID: https://orcid.org/0000-0003-1670-4435)
- Tomohiko Taniai (ORCID: https://orcid.org/0000-0001-8911-5530)
- Koichiro Haruki (ORCID: https://orcid.org/0000-0002-1686-3228)
- Michinori Matsumoto (ORCID: https://orcid.org/0000-0002-5860-1103)
- Toru Ikegami (ORCID: https://orcid.org/0000-0001-5792-5045)
- Mitsuru Yanagaki (ORCID: https://orcid.org/0000-0003-0664-5830)
- Yoshihiro Shirai (ORCID: https://orcid.org/0000-0002-4907-0101)
- Kohei Okazaki (ORCID: https://orcid.org/0009-0004-1387-111X)
- Yuna Saito
- Haruka Kobayashi (ORCID: https://orcid.org/0009-0007-6315-3660)
Institutions
- Jikei University School of Medicine (JP)
- Saku Central Hospital Advanced Care Center (JP)
Publication Details
- Journal
- World Journal of Surgery
- Published
- 2026-11-02
- DOI
- https://doi.org/10.1002/wjs.70666
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00