Controversy: Atrial fibrillation ablation should be performed in patients with HFpEF

Abstract The role of atrial fibrillation (AF) ablation in the management of heart failure with preserved ejection fraction (HFpEF) remains an under investigated issue with no robust clinical trials data. This controversy reviews the evidence for and against AF ablation in this complex condition from two different perspectives reviewing mechanistic and observational evidence aswell as proposing future directions for research in the field.

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Publication Details

Journal
EP Europace
Published
2026-11-04
DOI
https://doi.org/10.1093/europace/euag313
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Controversy: Atrial fibrillation ablation should be performed in patients with HFpEF

Pier David Lambiase, Luigi Di Biase, Matthew M Y Lee, Fengwei Zou et al.
EP Europace
Atrial Fibrillation Management and Outcomes
article

Controversy: Atrial fibrillation ablation should be performed in patients with HFpEF

Pier David Lambiase, Luigi Di Biase, Matthew M Y Lee, Fengwei Zou, Carolyn S.P. Lam
article en

Abstract

Abstract The role of atrial fibrillation (AF) ablation in the management of heart failure with preserved ejection fraction (HFpEF) remains an under investigated issue with no robust clinical trials data. This controversy reviews the evidence for and against AF ablation in this complex condition from two different perspectives reviewing mechanistic and observational evidence aswell as proposing future directions for research in the field.

EP Europace
Montefiore Medical Center (US), National University of Singapore (SG), British Heart Foundation (GB), Baim Institute for Clinical Research (US), Duke-NUS Medical School (SG), National Heart Centre Singapore (SG), University College London (GB), University of Glasgow (GB)
Good health and well-being
Openalex Percentile: Top 13%
Atrial Fibrillation Management and Outcomes
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