The Contour Neurovascular System Versus Woven Endobridge for Endovascular Embolization of Cerebral Aneurysms: A Propensity Score-matched Cohort Study

BACKGROUND AND OBJECTIVES: The Woven Endobridge (WEB) and the Contour Neurovascular System (Contour) are both intrasaccular devices used to treat cerebral aneurysms. We compared outcomes of these 2 devices using data from 2 large registries. METHODS: Data were sourced from the WorldWideWEB Consortium, which included 1363 cases treated with WEB from 2017, and a registry of 277 Contour cases from 10 European centers starting the same year. Patient demographics, aneurysm characteristics, procedural specifics, and outcomes were analyzed. Propensity score matching was applied for comparison. RESULTS: Before matching, the Contour group had more men (37.9% vs 30.8%), more asymptomatic cases (83.4% vs 70.3%), and fewer acute subarachnoid hemorrhage cases (10.8% vs 26.2%). After matching, no significant differences were found in demographics or aneurysm characteristics between groups. The median age was 60 years, and median aneurysm dimensions were comparable. Logistic regression showed no significant differences between WEB and Contour in achieving complete occlusion (odds ratio [OR] = 1.01, 95% CI, 0.67-1.52, P = .971), adequate occlusion (OR = 0.85, 95% CI, 0.41-1.76, P = .665), or achieving modified Rankin Scale 0 to 2 at last follow-up (OR = 0.48, 95% CI, 0.21-1.02, P = .064). Retreatment (OR = 2.23, P = .086), thromboembolic complications (OR = 0.75, P = .452), and adjunctive treatment use (OR = 1.93, P = .141) were also similar. CONCLUSION: The WEB and Contour demonstrated comparable clinical and angiographic outcomes in this large multicenter study comprised majority small, asymptomatic cerebral aneurysms.

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Journal
Neurosurgery
Published
2026-11-02
DOI
https://doi.org/10.1227/neu.0000000000004283
Primary Topic
Intracranial Aneurysms: Treatment and Complications
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article
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article

The Contour Neurovascular System Versus Woven Endobridge for Endovascular Embolization of Cerebral Aneurysms: A Propensity Score-matched Cohort Study

Sunil A. Sheth, Franziska Dorn, Fritz Wodarg, Joshua S. Catapano et al.
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Neurosurgery
Intracranial Aneurysms: Treatment and Complications
article

The Contour Neurovascular System Versus Woven Endobridge for Endovascular Embolization of Cerebral Aneurysms: A Propensity Score-matched Cohort Study

Sunil A. Sheth, Franziska Dorn, Fritz Wodarg, Joshua S. Catapano, Mohamed M. Salem, Eytan Raz, Sal Lamin, Thien J Huynh, Jose Danilo Bengzon Diestro, Ajit S Puri, Pedro Nicolas Lylyk, Constantin Hecker, Oktay Algın, Benjamin Pulli, Vedran Župančić, Muhammad Ubaid Hafeez, Markus Alfred Möhlenbruch, Neil Haranhalli, Guillaume Saliou, Mark E. Ogilvie, Jan‐Karl Burkhardt, Christoph Johannes Griessenauer, Hamza Adel Salim, Thomas Liebig, Sovann Vathana Lay, Elad I. Levy, Charlotte Y. Chung, Pietro Panni, James David Rabinov, Stavropoula I. Tjoumakaris, Nimer Adeeb, Juan Carlos Martínez-Gutiérrez, David Altschul, Christopher J. Stapleton, Rabih G. Tawk, Kareem El Naamani, Paul M. Foreman, Muhammed Amir Essibayi, Boris Lubicz, Srikanth Reddy Boddu, Clemens Maria Schirmer, Tufail F. Patankar, Iván Lylyk, Nicole Mariantonia Cancelliere, Anna Luisa Kühn, Adam Andrew Dmytriw, Sherief A. Ghozy, Waleed Brinjikji, Anh Nguyên, Diana E Slawski, Christian Ulfert, Nicola Limbucci, Joseph A. Carnevale, Caterina Michelozzi, Marie Teresa Nawka, Robert William Regenhardt, Pascal M. Jabbour, Frédéric Clarençon, Vladimir Kalousek, Felipe C. Albuquerque, Panagiotis Mastorakos, Marios‐Nikos Psychogios, Peter Bernhard Sporns, Gıyas Ayberk, Monika Killer‐Oberpfalzer, Michael Kral, Mario Martínez‐Galdámez, Vítor Mendes Pereira, Hugo Cuellar, Christophe Cognard, Hamed Asadi, Jared Knopman, Adrien Guenego, Mariangela Piano, Basel Musmar, Muhammad Waqas, Robert M. Starke, Andrew F. Ducruet, Adnan H. Siddiqui, Hamza Shaikh, Bryan Anthony Pukenas, Jens Fiehler, Peter Kan, Mohammad Bader Abuzahra, Alessandra Biondi, Leonardo Renieri, Yifan Ren, Ameer E. Hassan, Aman B. Patel, Ozgür Ozates, Guglielmo Pero, Eimad Shotar, Jesse Jones
article en

Abstract

BACKGROUND AND OBJECTIVES: The Woven Endobridge (WEB) and the Contour Neurovascular System (Contour) are both intrasaccular devices used to treat cerebral aneurysms. We compared outcomes of these 2 devices using data from 2 large registries. METHODS: Data were sourced from the WorldWideWEB Consortium, which included 1363 cases treated with WEB from 2017, and a registry of 277 Contour cases from 10 European centers starting the same year. Patient demographics, aneurysm characteristics, procedural specifics, and outcomes were analyzed. Propensity score matching was applied for comparison. RESULTS: Before matching, the Contour group had more men (37.9% vs 30.8%), more asymptomatic cases (83.4% vs 70.3%), and fewer acute subarachnoid hemorrhage cases (10.8% vs 26.2%). After matching, no significant differences were found in demographics or aneurysm characteristics between groups. The median age was 60 years, and median aneurysm dimensions were comparable. Logistic regression showed no significant differences between WEB and Contour in achieving complete occlusion (odds ratio [OR] = 1.01, 95% CI, 0.67-1.52, P = .971), adequate occlusion (OR = 0.85, 95% CI, 0.41-1.76, P = .665), or achieving modified Rankin Scale 0 to 2 at last follow-up (OR = 0.48, 95% CI, 0.21-1.02, P = .064). Retreatment (OR = 2.23, P = .086), thromboembolic complications (OR = 0.75, P = .452), and adjunctive treatment use (OR = 1.93, P = .141) were also similar. CONCLUSION: The WEB and Contour demonstrated comparable clinical and angiographic outcomes in this large multicenter study comprised majority small, asymptomatic cerebral aneurysms.

Neurosurgery
Louisiana State University (US), Leeds General Infirmary (GB), St. Michael's Hospital (CA), Albert Einstein College of Medicine (US), UMass Memorial Health Care (US), Barrow Neurological Institute (US), Mayo Clinic (US), Montefiore Medical Center (US), NewYork–Presbyterian Hospital (US), The University of Texas MD Anderson Cancer Center (US), University of Bonn (DE), Harvard University (US), University of Miami (US), Orlando Health (US), Ankara University (TR), University of Toronto (CA), Louisiana State University in Shreveport (US), Paracelsus Medical University (AT), Queen Elizabeth Hospital Birmingham (GB), Thomas Jefferson University Hospital (US), Austin Hospital (AU), Erasmus Hospital (BE), University Hospital Heidelberg (DE), Centre Hospitalier Universitaire Vaudois (CH), The University of Texas Rio Grande Valley (US), University Hospital of Basel (CH), LMU Klinikum (DE), Centre Hospitalier Universitaire de Toulouse (FR), University of Alabama at Birmingham (US), University of Oxford (GB), NYU Langone Health (US), Massachusetts General Hospital (US), Centre Hospitalier Universitaire de Besançon (FR), Hospital La Luz (ES), Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT), Christian Doppler Klinik (AT), University Medical Center Hamburg-Eppendorf (DE), University Hospital Schleswig-Holstein (DE), Azienda Ospedaliero-Universitaria Careggi (IT), Pitié-Salpêtrière Hospital (FR), Sisters of Charity Hospital (HR), IRCCS Ospedale San Raffaele (IT), Stanford Medicine (US), Mayo Clinic in Florida (US), Ankara Yıldırım Beyazıt University (TR), Hospital Clínico Universitario de Valladolid (ES), UMass Memorial Medical Center (US), Austin Health (AU), Weill Cornell Medicine (US), Laboratoire de recherches Intégratives en Neurosciences et psychologie Cognitive (FR), UAB Medicine (US), IDCQ Hospitales y Sanidad, S.L.U. (ES), Weill Cornell Medical Center (US), Toronto Metropolitan University (CA), Geisinger Health System (US), The University of Texas Medical Branch at Galveston (US), University at Buffalo, State University of New York (US), University of Pennsylvania (US), Ludwig-Maximilians-Universität München (DE), Université de Franche-Comté (FR), The University of Texas Health Science Center at Houston (US), Stanford University (US)
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Intracranial Aneurysms: Treatment and Complications
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