Orch-OR Still Unfalsified: Indirect 2024–2025 Evidence, No Decisive In-Vivo Test — E8 Intelligence Research

FINDING: Orch-OR remains unfalsified but lacks direct in-vivo confirmation; 2024–2025 evidence is indirect (anesthetic binding, microtubule coherence, superradiance) — no new decisive experiment. | MATH: Core formalism: gravitational self-energy of superposition E_Δ = ħ/τ (Diósi–Penrose), collapse time τ ≈ ħ/E_Δ; E_Δ = (G/2)∫∫ (ρ₁−ρ₂)(ρ₁'−ρ₂')/|r−r'| d³r d³r'. Tubulin dimer mass m ≈ 110 kDa ≈ 1.83×10⁻²² kg; superposition displacement Δx ~ nm scale → τ ~ 10⁻² to 10⁻¹ s (Hameroff's "40 Hz" claim). | CONNECTION: Microtubule lattice = 13 protofilament helical B-lattice, pitch ratios ~ 3:5:8 (Fibonacci-adjacent), A/B tubulin staggering ~ 0.9 nm; 13-fold helical symmetry is not a standard crystallographic point group (it's a screw axis 13₅). No confirmed 0.618/1.618 ratio in the collapse math. | DEPTH: 4 FINDING: Tegmark's decoherence objection (2000) still stands quantitatively; 2024 rebuttals invoke Debye screening + coherent water layers but do not close the gap. | MATH: Tegmark decohere Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com