Optimizing Dry Eye Management: An Expert Consensus on the Use of Sodium Hyaluronate at Different Concentrations
Background: Dry eye disease (DED) is a common, multifactorial disorder that affects ocular comfort and visual quality.Despite widespread use of sodium hyaluronate (SH) as a lubricant, the selection of appropriate SH concentration and formulation for different stages of DED has not been standardized in India.Methods: This expert consensus was developed through a modified Delphi process with 23 renowned ophthalmologists reviewing available evidence and forming consensus statements on diagnosis, SH concentration, preservative-free options, dosing, and unmet needs.Results: The panel recommended a stepwise approach: 0.1% SH for mild disease, 0.18% SH for moderate disease balancing efficacy and comfort, and preservative-free 0.3% SH for moderate-to-severe or postsurgical DED.The experts also emphasized the importance of preservative-free formulations, individualized dosing schedules, and patient education to ensure sustained symptom relief and adherence.Conclusion: The purpose of this consensus is to unify practice and guide evidence-based management of DED in India.
Authors
- Ashish Majumdar (ORCID: https://orcid.org/0000-0002-8519-0792)
- Onkar C Swami (ORCID: https://orcid.org/0000-0001-6006-7520)
- Piyali Konar
- Raj Shekhar Paul (ORCID: https://orcid.org/0000-0003-4520-7454)
- Rishi Swarup
- Chandni Chakraborty
- Shoumya Jyoti Datta Mazumder
- Vedang Shah (ORCID: https://orcid.org/0000-0002-5990-9564)
- Subhratanu Chakrabarty
- Divya Jain (ORCID: https://orcid.org/0000-0001-9814-6291)
- Arjun Srirampur
- Ayan Mitra (ORCID: https://orcid.org/0009-0006-8719-9973)
- Ritu Agarwal
- Rama Raju Venkata Sesha Kalyani
- Bindiya Deepak Wadhwa
- K Harshitha
- Bindumadhavi Manapragada
- Bejugam Pranathi
- Amith Kumar Polu
- V Latha
- Soumya Kundu
- Dinesh Patil
- Katikaneni Priyanka
- STS Pridhu Vyas
Publication Details
- Journal
- Cureus
- Published
- 2026-11-01
- DOI
- https://doi.org/10.7759/cureus.118969
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 0.00