A Case of Delayed-Onset, Apomorphine-Induced Haemolytic Anaemia

We present a case of apomorphine-induced haemolytic anaemia in a 72-year-old female patient with Parkinson's disease.Of note, the adverse drug reaction was delayed-onset, occurring three and a half years after commencing the apomorphine infusion.The diagnosis was based on clinical suspicion and supported by immunohaematological testing, including direct Coombs' test, antibody testing and a characteristic blood film.Early recognition and cessation of the drug were critical in the management of the patient.The case highlights the importance of adequate monitoring while on continuous apomorphine to ensure early detection of adverse drug reactions.

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Publication Details

Journal
Cureus
Published
2026-11-02
DOI
https://doi.org/10.7759/cureus.119010
Primary Topic
Blood groups and transfusion
Type
article
Field-Weighted Citation Impact
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article

A Case of Delayed-Onset, Apomorphine-Induced Haemolytic Anaemia

Sophie C Bowden, Daniel Logue
1 links
Cureus
Blood groups and transfusion
article

A Case of Delayed-Onset, Apomorphine-Induced Haemolytic Anaemia

Sophie C Bowden, Daniel Logue
article en

Abstract

We present a case of apomorphine-induced haemolytic anaemia in a 72-year-old female patient with Parkinson's disease.Of note, the adverse drug reaction was delayed-onset, occurring three and a half years after commencing the apomorphine infusion.The diagnosis was based on clinical suspicion and supported by immunohaematological testing, including direct Coombs' test, antibody testing and a characteristic blood film.Early recognition and cessation of the drug were critical in the management of the patient.The case highlights the importance of adequate monitoring while on continuous apomorphine to ensure early detection of adverse drug reactions.

Cureus
Northern Health and Social Care Trust (GB)
Good health and well-being
Openalex Percentile: Top 13%
Blood groups and transfusion
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