Acanthamoeba Keratitis: When Presumed Herpes Isn't Herpes

Acanthamoeba keratitis (AK) is uncommon, but missing the diagnosis can have devastating consequences. The early clinical picture is often non-specific, and the disease can closely mimic herpes simplex keratitis (HSK). For any clinician assessing a contact lens wearer with keratitis, keeping Acanthamoeba a part of the differentials is therefore essential.