PHARMACEUTICAL STUDY ON DEVELOPMENT OF NOOLA MALAHARA - TOPICAL DOSAGE FORM

Background: Noola Taila, described by Acharya Vangasena in the context of Agantuka Vrana Rogadhikara, is a medicated oil of the Sneha Kalpana group used for wounds and is attributed with Vrana Ropana (wound healing) activity. Its application in the form of Noola Malahara is intended for the management of Parikartika. Objective: Noola Malahara was formulated as a semisolid dosage form using Noola Taila as the base material. Methods: A Kwatha was prepared from coarse powder of Bala moola (2 kg) and Apamarga moola (2 kg) with 8 parts of water, reduced to one-fourth. This was boiled with Tila taila (2 litres) on mild fire with continuous stirring until Sneha siddhi lakshana appeared. Noola Malahara was then prepared as per the Malahara Kalpana of Rasatarangini by adding Sikta (390 g) to hot Noola Taila (1950 ml) in a 1:5 ratio. Results: For the preparation of Noola Malahara, 390 g of Sikta was added to the hot Noola Taila and thoroughly mixed. The mixture was allowed to stand for approximately 30 minutes to facilitate proper mixing and setting. A total of 32 tubes of Noola Malahara were prepared, with each tube containing approximately 45 g of Malahara. Conclusion: Classical Ayurvedic methods can be applied to prepare Noola Taila and its Malahara form. Further clinical evaluation is recommended to establish its efficacy in wound healing and anorectal disorders such as Parikartika.