IL-1b contributes to cardiovascular disease in man.
High CRP is one the few known indicators of elevated risk for heart attack and cardiovascular disease. We present a hypothesis suggesting an elevated background level of the pro-inflammatory cytokine IL-1b supports cardiovascular disease. We demonstrate by studying total transcription in the blood in humans with low and high CRP that interleukin-1b is specifically enriched in the blood of humans with high CRP.
Authors
- Shahan Mamoor (ORCID: https://orcid.org/0000-0003-4150-0936)
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2026-11-01
- DOI
- https://doi.org/10.5281/zenodo.23862479
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- preprint