Prehospital physiological parameters associated with acute thoracic intervention in patients with thoracic trauma: a retrospective single-centre cohort study

Abstract Purpose Thoracic trauma can cause life-threatening respiratory and hemodynamic compromise. We examined associations between prehospital physiological parameters and acute thoracic intervention in patients with thoracic trauma. Methods This retrospective TraumaRegister DGU® cohort study was conducted at a level I trauma centre (2018–2022). Adults with thoracic trauma were included; patients undergoing prehospital cardiopulmonary resuscitation were excluded. Thoracic intervention comprised prehospital decompression and/or emergency department chest tube placement. Logistic regression and receiver operating characteristic analyses were performed. Results Among 387 patients, 104 (26.9%) underwent intervention. In the primary model (n = 317), lower oxygen saturation (SpO₂) (adjusted odds ratio [OR] per percentage-point increase, 0.949; 95% confidence interval [CI], 0.913–0.986) and penetrating trauma (adjusted OR, 9.163; 95% CI, 2.735–30.699) were associated with intervention. In the exploratory alternative model (n = 277), higher respiratory rate was also associated with intervention (adjusted OR per breath/min, 1.071; 95% CI, 1.010–1.135); associations with SpO₂ and penetrating trauma persisted. SpO₂ discrimination was limited (area under the curve, 0.610; 95% CI, 0.540–0.680). Conclusion Lower SpO₂ and penetrating trauma were associated with thoracic intervention in the primary model; higher respiratory rate was additionally associated in the exploratory alternative model. Because SpO₂ had limited discriminatory ability, it should not be used alone to guide decisions about thoracic intervention.

Authors

Institutions

Publication Details

Journal
Research Square
Published
2026-11-01
DOI
https://doi.org/10.21203/rs.3.rs-11333441/v1
Primary Topic
Trauma Management and Diagnosis
Type
preprint
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
preprint

Prehospital physiological parameters associated with acute thoracic intervention in patients with thoracic trauma: a retrospective single-centre cohort study

Martin Breitkopf, Christian Knop, Lukas Reccius, Tomas Da Silva
1 links
Research Square
Trauma Management and Diagnosis
preprint

Prehospital physiological parameters associated with acute thoracic intervention in patients with thoracic trauma: a retrospective single-centre cohort study

Martin Breitkopf, Christian Knop, Lukas Reccius, Tomas Da Silva
preprint en

Abstract

Abstract Purpose Thoracic trauma can cause life-threatening respiratory and hemodynamic compromise. We examined associations between prehospital physiological parameters and acute thoracic intervention in patients with thoracic trauma. Methods This retrospective TraumaRegister DGU® cohort study was conducted at a level I trauma centre (2018–2022). Adults with thoracic trauma were included; patients undergoing prehospital cardiopulmonary resuscitation were excluded. Thoracic intervention comprised prehospital decompression and/or emergency department chest tube placement. Logistic regression and receiver operating characteristic analyses were performed. Results Among 387 patients, 104 (26.9%) underwent intervention. In the primary model (n = 317), lower oxygen saturation (SpO₂) (adjusted odds ratio [OR] per percentage-point increase, 0.949; 95% confidence interval [CI], 0.913–0.986) and penetrating trauma (adjusted OR, 9.163; 95% CI, 2.735–30.699) were associated with intervention. In the exploratory alternative model (n = 277), higher respiratory rate was also associated with intervention (adjusted OR per breath/min, 1.071; 95% CI, 1.010–1.135); associations with SpO₂ and penetrating trauma persisted. SpO₂ discrimination was limited (area under the curve, 0.610; 95% CI, 0.540–0.680). Conclusion Lower SpO₂ and penetrating trauma were associated with thoracic intervention in the primary model; higher respiratory rate was additionally associated in the exploratory alternative model. Because SpO₂ had limited discriminatory ability, it should not be used alone to guide decisions about thoracic intervention.

Research Square
Klinikum Stuttgart (DE)
Good health and well-being
Trauma Management and Diagnosis
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Laika access coming soon
Prehospital physiological parameters associated with acute thoracic intervention in patients with thoracic trauma: a retrospective single-centre cohort study — Martin Breitkopf, Christian Knop, et al. · Research Square (2026) | TGRS Research Map | TGRS