Using Kif genes as a generic metric for understanding the effect of variant expression in human cells.

The approach, using an approximation or overall profile of the change in expression of all Kif genes between wild-type and diseased or mutant condition, as a generic metric for understanding the effect of variant expression in human cells, has promise in describing with detail mechanism of action in human disease by profiling mutation or variant by cytoskeletal, cycling and asymmetric cell division phenotype.