Pediatric Bronchospasm: Pathophysiology, Etiology, Evaluation, and Interprofessional Management

Bronchospasm represents a cardinal pathophysiological phenomenon in pediatric respiratory medicine, characterized by acute smooth muscle constriction of the small airways with resultant airflow limitation. The pediatric population exhibits heightened susceptibility to bronchospastic disease due to unique anatomical and physiological characteristics, including smaller airway calibers, distinct lung mechanics, and developmental differences in chest wall compliance. This comprehensive review examines the principal etiologies of pediatric bronchospasm—acute asthma exacerbation, acute viral bronchiolitis, and anaphylaxis—while also addressing foreign body aspiration and vascular ring as important diagnostic considerations. The discussion encompasses epidemiological patterns, clinical presentation, diagnostic evaluation, and evidence-based management strategies. Special emphasis is placed on the application of Poiseuille's Law to airway resistance, the pathophysiological mechanisms underlying each disease process, and the critical importance of interprofessional collaboration in optimizing patient outcomes. The review synthesizes current evidence to provide clinicians with a structured framework for recognizing, evaluating, and managing pediatric bronchospasm across the continuum of care.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-11-01
DOI
https://doi.org/10.5281/zenodo.23862205
Primary Topic
Asthma and respiratory diseases
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Pediatric Bronchospasm: Pathophysiology, Etiology, Evaluation, and Interprofessional Management

Indunil Karunarathna, Asoka Karunarathna
3 links
Zenodo (CERN European Organization for Nuclear Research)
Asthma and respiratory diseases
article

Pediatric Bronchospasm: Pathophysiology, Etiology, Evaluation, and Interprofessional Management

Indunil Karunarathna, Asoka Karunarathna
article en

Abstract

Bronchospasm represents a cardinal pathophysiological phenomenon in pediatric respiratory medicine, characterized by acute smooth muscle constriction of the small airways with resultant airflow limitation. The pediatric population exhibits heightened susceptibility to bronchospastic disease due to unique anatomical and physiological characteristics, including smaller airway calibers, distinct lung mechanics, and developmental differences in chest wall compliance. This comprehensive review examines the principal etiologies of pediatric bronchospasm—acute asthma exacerbation, acute viral bronchiolitis, and anaphylaxis—while also addressing foreign body aspiration and vascular ring as important diagnostic considerations. The discussion encompasses epidemiological patterns, clinical presentation, diagnostic evaluation, and evidence-based management strategies. Special emphasis is placed on the application of Poiseuille's Law to airway resistance, the pathophysiological mechanisms underlying each disease process, and the critical importance of interprofessional collaboration in optimizing patient outcomes. The review synthesizes current evidence to provide clinicians with a structured framework for recognizing, evaluating, and managing pediatric bronchospasm across the continuum of care.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 13%
Asthma and respiratory diseases
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Laika access coming soon